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This study found that a single dose of TRP significantly reduced the number of UV-B-induced actinic keratosis lesions in a mouse model and was associated with improved skin histology and minimal side effects.

This study developed a highly sensitive fluorescent assay for measuring enzyme activity in single hair follicles, allowing the efficient analysis of over 100 samples per day.

This study found that paclitaxel poliglumex showed limited effectiveness and was relatively well tolerated in post-menopausal women with advanced NSCLC, suggesting further testing of this treatment may not be justified.

This article reviews trichoscopic techniques for diagnosing common hair loss conditions and presents a revised algorithm for identifying specific features of cicatricial and noncicatricial alopecia, but reports no new clinical results.

This study observed that discontinuation rates due to side effects were similar for penicillamine and tiopronin among cystinuria patients, and switching to the alternative agent was beneficial for half of those experiencing issues.

This case study reports a teenage boy with juvenile polyposis syndrome, presenting with microcytic anemia, growth failure, and rectal bleeding, leading to the diagnosis following colonoscopy and histologic examination of colonic polyps.

This article discusses topical and intralesional cidofovir use for SCC and suggests a successful outcome in one case, with no systemic toxicity observed so far.

In this study, the Tibot AI application showed high diagnostic accuracy for adnexal and pigmentary disorders and cutaneous tumors in dermatology, but was less effective for immunological disorders and infestations, suggesting the need for further dataset refinement.

This study found that chromosomal microarray analysis identified copy number variations in 12% of patients with dysmorphic features and congenital anomalies, demonstrating its potential as a diagnostic tool, especially for rare CNVs and immune deficiency linked to the deletion of CTLA4.

Some medications for inflammation can cause a condition with scalp rashes and hair loss, often linked to Crohn's disease, and may require treatment changes to prevent permanent hair loss.

This case report details two consanguineous patients with cerebral autosomal recessive arteriopathy, both having the same HTRA1 gene mutation, but exhibiting different clinical presentations, including one with epileptic seizures and lobar hemorrhages—previously undocumented in this condition.

This study identified a coexpression network and key genes associated with thyroid eye disease, potentially aiding in its treatment and diagnosis.

CD10 helps distinguish between basal cell carcinoma and benign hair follicle tumors.

This study demonstrated that transcutaneous vaccination via cyanoacrylate skin surface stripping effectively induced both CD4 and CD8 T cell responses in humans, offering a promising alternative to intramuscular injection.

This study found that adults with trichotillomania did not show differences in pain tolerance or exhibit analgesia to cold pressor pain compared to healthy controls.

In this case study, treatment with terbinafine effectively resolved symptoms of tinea capitis in an eight-year-old male, highlighting trichoscopy as a valuable diagnostic tool for this common fungal scalp infection and proposing its integration with clinical data for quicker diagnosis in settings lacking mycological facilities.

This review discusses the use of trichoscopy as a valuable diagnostic and prognostic tool for various hair and scalp disorders, reporting no new clinical results.

In this study, the authors evaluated 200 Egyptian children with focal non-cicatricial alopecia, finding that alopecia areata (42%) and tinea capitis (40.5%) were the most prevalent causes. Trichoscopy identified unique features for each condition, enhancing diagnosis and management.

This study compared oral tofacitinib and methotrexate in treating moderate-to-severe alopecia areata, finding that tofacitinib was more effective at reducing SALT scores and improving scalp hair assessment PRO scores, though both treatments reduced psychological distress similarly without serious adverse effects.

This document provides a legal disclaimer and offers no research findings.

This review discusses the development and potential therapeutic applications of steroid sulfatase inhibitors for hormone-dependent disorders and cognitive dysfunction, reporting no new clinical results.

This study observed that basal cell carcinomas with matrical differentiation may derive from hair follicles, with .-catenin potentially playing a key role in tumor development and differentiation.

This case report describes a Thai male with TRPS1 who exhibited unique and unreported features such as hypoplastic mandibular condyles, double mental foramina, and distinctive hair abnormalities.

This study suggests that the CsA-induced inactivation of the CaN/NFAT pathway may suppress TGF-β2 expression in dermal papilla cells, potentially contributing to CsA-associated hypertrichosis.

This review consolidates current knowledge about Cronkhite-Canada syndrome, highlighting its symptoms, diagnostic challenges, and evolving treatment strategies, but reports no new clinical results.

In this case report, a 16-year-old female with Netherton syndrome, a rare genetic disorder, exhibited symptoms such as skin issues, hair abnormalities, and elevated serum IgE levels. The diagnosis was supported by skin biopsy, and treatment included topical therapies, NB-UVB, and infliximab.

This review examines patents and publications on steroid sulfatase inhibitors since 1999 and reports no new clinical results, highlighting their potential for treating estrogen- and androgen-driven conditions.

In this study, hair samples from breast cancer patients showed increased β-sheet structures and lipid content, with spectral markers successfully identifying cancer in a blind test but also producing false positives.

In this study, trichoscopy significantly improved diagnostic accuracy in non-cicatricial alopecia, identifying alopecia areata as the most common cause and effectively aiding diagnosis in 28.2% of ambiguous cases.

The study found that while a clinical protocol showed high specificity in detecting scrapie in goats, its low sensitivity suggests many cases might be missed if diagnosis is only based on clinical signs.