In this case report, researchers describe a 22-year-old male with a unique presentation of Senior-Løken Syndrome due to a NPHP4 mutation, exhibiting atypical symptoms like cryptorchidism, alopecia, and potential syndromic overlap with Rothmund-Thomson Syndrome, suggesting complex genetic interactions and expanding the phenotypic spectrum of ciliopathies.
This study found that tadalafil use was associated with a decreased risk of major adverse cardiac events and venous thromboembolism in men with lower urinary tract symptoms.
This abstract lists numerous dermatological side effects and reactions associated with various medications but reports no new research findings.
11 citations
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September 2015 in “Theriogenology” Testosterone boosts fluid and electrolyte secretion in seminal vesicles, aiding sperm function.
2 citations
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September 2024 in “PLoS ONE” This study suggests that combining bendamustine with tucidinostat may improve survival in patients with relapsed or refractory adult T-cell leukemia/lymphoma, highlighting its potential for clinical investigation.
This study concluded that removing alopecia and mucous membrane components from the CLASI-A score limits the ability to capture crucial clinical information about cutaneous lupus erythematosus activity, recommending their retention.
15 citations
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August 2011 in “Lasers in medical science” This study reported that a single treatment with a short-pulsed 755-nm alexandrite laser effectively treated trichostasis spinulosa in patients with skin types II to V, providing rapid results with minimal pain and no recurrence during a 3-month follow-up.
1 citations
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May 2024 in “Skin Appendage Disorders” This study describes trichoscopic findings in 11 dark-skinned women with central centrifugal cicatricial alopecia and highlights the potential of trichoscopy for early diagnosis and treatment.
March 1996 in “The American Journal of Cosmetic Surgery” This article describes a surgical technique combining CO2 SilkTouch Laser and Calvitron Hair Transplant System that offers a natural-looking hairline with moderate session length and minimal bleeding, but reports no new clinical outcomes.
April 2023 in “Journal of Investigative Dermatology” This study found that an automated tumor-infiltrating lymphocyte classification algorithm identified thin melanomas with less immune response, which were associated with higher mortality compared to other cases in the study.
21 citations
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January 2013 in “Clinical Endoscopy” This study reports the first case in South Korea of Cronkhite-Canada syndrome associated with malignant colon polyp and serrated adenoma.
6 citations
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March 2020 in “Anais Brasileiros de Dermatologia” This study found that the genetic variants rs231775 and rs3087243 of the CTLA4 gene are not associated with alopecia areata in the Mexican population analyzed.
32 citations
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August 2016 in “Journal of the American Academy of Dermatology” This letter discusses congenital triangular alopecia (TTA), a non-scarring hair loss condition often seen in children, without reporting new clinical findings.
15 citations
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March 1998 in “Journal of Public Policy & Marketing” This article discusses the development and testing of comprehensible over-the-counter drug product labels, highlighting the need for improved consumer understanding and calling for further research on label design.
December 2022 in “Gastroenterology” This report describes a case of Cronkhite-Canada syndrome diagnosed in a 54-year-old man with symptoms including gastrointestinal polyps, alopecia, skin hyperpigmentation, and severe diarrhea, who experienced significant symptom improvement with azathioprine.
28 citations
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December 2001 in “European Journal of Pharmacology” This study found that the compound M50054 inhibits apoptosis by blocking caspase-3 activation and may improve chemotherapy-induced alopecia and hepatitis symptoms.
14 citations
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February 1991 in “FEBS Letters” This study found that introducing rat ornithine transcarbamylase gene into spf-ash mice improved liver and intestinal enzyme activity and normalized some metabolic indicators.
14 citations
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January 2021 in “Scientific Reports” This study found that "micro skin tissue columns" improved wound healing by enhancing re-epithelialization, collagen deposition, dermal remodeling, and reducing inflammation without causing long-term donor site morbidity.
62 citations
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December 1941 in “Experimental biology and medicine” In this study, phenylthiocarbamide intake was associated with hair graying in rats, while switching to tap water led some rats to regain their original fur color, suggesting dietary factors influence pigmentation.
April 2025 in “BMC Chemistry” This study developed an organic hair conditioner using chitosan-thiadiazole conjugates that showed improved hair detangling, moisture retention, and protection without causing irritation, promising an environmentally sustainable approach to hair care.
January 2026 in “Diagnostics” This study reports that publicly available large language models are currently less accurate than human experts in diagnosing trichoscopic images, suggesting the need for further development and specialized training for these AI tools in trichology.
660 citations
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December 2011 in “Cell” This study found that distinct low-threshold mechanoreceptors innervate different hair follicle types in mice, suggesting that these follicles serve as unique mechanosensory structures in touch perception.
5 citations
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January 2024 in “Journal of Cancer” In this phase II clinical study, combining anlotinib with standard platinum-based chemotherapy showed promising outcomes and prognosis in treating extensive small-cell lung cancer, with high disease control and response rates.
14 citations
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January 2011 in “Journal of analytical & bioanalytical techniques” This research discusses a validated HPTLC method for simultaneously determining Tamsulosin Hydrochloride and Finasteride in bulk and pharmaceutical dosage forms but reports no new clinical results.
555 citations
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July 2001 in “Genes & Development” This study found that Tcf3 and Lef1 differently regulate cell differentiation in multipotent skin stem cells, with Tcf3 promoting follicle-like features and Lef1, when modified, promoting sebocyte differentiation.
25 citations
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October 2007 in “Developmental biology” In this study, transgenic mice altered to express a Clim-inhibiting molecule under a keratin promoter showed corneal degradation and hair follicle failure, highlighting Clim proteins' role in maintaining these tissues.
1 citations
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June 2015 in “Australasian Journal of Dermatology” This case report describes a patient with Cronkhite–Canada syndrome, where immunosuppression and nutritional support led to disease remission.
10 citations
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August 2022 in “Bulletin of Mathematical Biology” This study demonstrated that the Turing bifurcation, typically a pitchfork bifurcation under zero-flux conditions, becomes transcritical under fixed boundary conditions, highlighting the importance of considering boundary condition variations in morphogenetic analyses.
September 2026 in “Clinical Cosmetic and Investigational Dermatology” This case report highlights the diagnostic challenges in a patient with atypical lupus erythematosus tumidus due to long-term misdiagnosis and conflicting pathological findings, with effective treatment achieved using hydroxychloroquine and methylprednisolone.
13 citations
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January 2011 in “International Journal of Trichology” CTA is often mistaken for AA but doesn't respond to steroids and may require hair transplantation.