75 citations
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June 2019 in “International Journal of Molecular Sciences” This review discusses the therapeutic potential of costunolide for various diseases, highlighting its bioactivity and mechanisms, but it reports no new experimental results.
21 citations
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May 2018 in “Journal of Cosmetic Dermatology” This study found that costunolide promotes hair growth in both lab-cultured human hair follicle cells and in live mice by modulating growth factor pathways.
November 2025 in “Quantum Wellness : Jurnal Ilmu Kesehatan” This study analyzed the ethanol extract of pacing tawar leaves and found it contains alkaloids, saponins, tannins, and steroids but not flavonoids, suggesting potential for use in natural medicinal products.
October 2025 in “INSOLOGI Jurnal Sains dan Teknologi” In this laboratory study on rabbits, the researchers observed that both FET and FHE fractions improved hair length and weight, but minoxidil still led to better results, highlighting the comparative effects of different treatments on hair growth over 28 days.
34 citations
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April 2006 in “PubMed” This review discusses current treatments for benign prostatic hyperplasia and reports on the cost-effectiveness of alpha1-selective adrenergic receptor antagonists compared to other pharmacologic and invasive therapies without presenting new clinical results.
6 citations
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July 2022 in “Journal of health economics and outcomes research” This study found that US adolescents with alopecia areata, especially those with alopecia totalis or universalis, experience significantly higher healthcare costs and resource use compared to matched controls.
5 citations
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January 2019 in “Revista Latino-americana De Enfermagem” In this study, the direct cost of producing autologous platelet rich plasma gel in a Rio de Janeiro university hospital was found to be US $4.88 per session, highlighting its potential as a low-cost and accessible treatment option within the Unified Health System.
2 citations
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June 2017 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that honey marketing in Cross River State is profitable, but efficiency is hindered by challenges like high transportation costs and lack of capital.
November 2025 in “Urology” This study found that the Mark Cuban Cost Plus Drug Company offers significant cost savings on men's health medications compared to both Medicare and GoodRx, particularly for erectile dysfunction treatments.
April 2023 in “Journal of Investigative Dermatology” This study found that adults with atopic dermatitis who were treated with baricitinib at doses of 2mg or 4mg experienced significant improvements in work productivity, potentially leading to substantial indirect cost savings for employers over 16 weeks.
119 citations
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November 2014 in “Trends in Cell Biology” This review discusses the mechanisms and pathways of FGFR signalling and its roles in development, disorders, and therapeutic targeting, but reports no new clinical results.
4 citations
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July 2022 in “Journal of health economics and outcomes research” This review discusses the economic burden of alopecia areata in adolescents and reports no new results; the authors note that evidence in this area is limited.
3 citations
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March 2023 in “Journal of Medical Economics” This study found that middle-aged patients, patients in certain geographical regions, and female patients of specific age groups with alopecia areata face higher medical costs, indicating significant financial variability for affected subgroups.
1 citations
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January 2023 in “Acta dermato-venereologica” This study found that individuals with alopecia areata in Germany, Austria, and Switzerland face significant out-of-pocket costs averaging 1,248€ annually, primarily for hair replacement products and cosmetics.
November 2025 in “The Journal of Sexual Medicine” This study found that the Mark Cuban Cost Plus Drug Company model offers substantial cost savings on men's health medications compared to Medicare and GoodRx, particularly for long-term treatments.
November 2025 in “Journal of Investigative Dermatology” This review highlights that alopecia areata significantly impacts mental health and finances, with patients facing depression, anxiety, and substantial out-of-pocket expenses due to limited insurance coverage.
September 2024 in “Journal of the American Academy of Dermatology” Botulinum toxin is not effective or cost-efficient for treating male pattern baldness.
November 2025 in “Research Repository UCD (University College Dublin)” This paper analyzes the representation of baldness in contemporary screen media, arguing that it reflects and perpetuates societal anxieties about masculinity, aging, and power, portraying hair loss as a disorder requiring intervention despite its natural occurrence and lack of health risks.
September 2024 in “Journal of the American Academy of Dermatology” Botulinum toxin is not effective for treating male hair loss.
April 2022 in “Urology Practice” This study found that sociodemographic factors influence the likelihood of recurrent urinary retention episodes and the decision to undergo bladder outlet procedures, with only 6.4% of patients receiving such procedures despite their potential cost benefits.
17 citations
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January 2015 in “Pharmacognosy Research” In this study, the herbal hair colorant formulation HD-3, with a mix of specific herbs, was most effective at coloring hair and highly accepted by volunteers.
12 citations
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October 2021 in “Cells” This review discusses the potential of miRNA-mediated hair growth treatments for androgenetic alopecia by targeting DKK1 to modulate the Wnt/β-catenin signaling pathway and reports no new clinical findings.
10 citations
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March 2023 in “Journal of Managed Care & Specialty Pharmacy” This study found that patients with alopecia areata had similar total health care costs as those with atopic dermatitis, despite having fewer comorbidities and prescription medications overall.
November 2024 in “Image Analysis & Stereology” This study introduced a novel, weakly supervised method for segmenting hair in Scanning Electron Microscope images using simple image-level annotations, achieving over 30% improvement in mean Hausdorff Distance compared to Unet and SAM, while enhancing interpretability and refinement.
September 2024 in “JEADV Clinical Practice” In this study, researchers analyzed French social media posts and found that alopecia areata profoundly impacts patients' quality of life, affecting them physically, psychologically, socially, and financially, often driving them to seek support online.
November 2010 in “Value in Health” Treating chronic hand eczema costs about the same in statutory and occupational health insurances in Germany, but work-related cases may lead to higher indirect costs due to longer work absences.
3 citations
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January 2024 in “Preprints.org” This study estimated the economic burden of alopecia areata in Romania for 2022, finding costs of 46.289 million EUR for adult and 1.89 million EUR for pediatric cases.
May 2014 in “Journal of The American Academy of Dermatology” Psoriasis increases annual healthcare costs by $4,044 per patient, with biologic treatments costing significantly more than phototherapy.
February 2026 in “Journal of Craniofacial Surgery Open” This narrative review outlines the biological costs of hair extensions, such as traction leading to hair loss and scalp issues, and suggests a prevention-focused model involving risk assessment, surveillance, and tiered therapies to minimize alopecia risk and maintain scalp health.