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Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

People distressed by minor skin changes should consult dermatologists with cosmetic expertise, and a public Cosmetic Dermatology Service with mental health support is recommended.

Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.

Melampus might have cured Proetus' daughters, who possibly had ergotism or Cushing's syndrome, using the herb Helleborus niger, but a mix of factors could have caused their symptoms.

Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.

A woman with Cushing's syndrome improved after surgery to remove a tumor causing the condition.

People with Parkinson's disease have higher levels of cortisone in their hair, which may indicate chronic stress hormone dysfunction.

A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and budesonide, which improved after stopping the medications.

A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and inhaled budesonide.

ARL15 is important for fat cell development and the release of the hormone adiponectin.

A patient produced cortisol after adrenalectomy, possibly due to residual tissue or other body parts making steroids.

Hair cortisol may be a good indicator of recent mood in people with bipolar disorder.

Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.

Greek women with classic PCOS are more likely to have metabolic syndrome and insulin resistance than those with newer PCOS types.

Scalp hair sweating is a significant predictor of hair cortisol levels.

Hair cortisol is a reliable marker of long-term cortisol levels and is linked to daytime saliva cortisol but not morning levels.

Elephant tail-hair can show past stress levels, matching times when stressful events happened.

High levels of cortisol in hair are linked to a greater risk of brain aneurysm rupture.

High hair cortisol levels indicate stress in cows due to poor shelter conditions and health issues.

Pigs in farrowing crates and loose-housing systems showed no difference in chronic stress levels as measured by hair cortisol.

Nourkrin® with Marilex® may significantly increase hair growth and alopecia could be an early sign of metabolic syndrome.

Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.

Shift nurses show altered body temperature and stress hormone levels, suggesting their body clocks adjust to irregular schedules.

Human leukocytes and beard hair follicle cells have internal daily clocks, and PER1 and PER3 genes may indicate individual circadian rhythms.

The document concludes that diagnosing and treating Congenital Adrenal Hyperplasia is complex and requires a team approach due to its effects on the skin and other symptoms.

A postmenopausal woman's increased male hormone levels were successfully treated with surgery.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Primary care for PCOS focuses on lifestyle changes, medication based on symptoms, and mental health, with diabetes screening and specialist referral for severe cases.