July 2021 in “Advances in laboratory medicine” This article reviews differential diagnosis approaches for 46,XY DSD, proposing a diagnostic algorithm focused on biochemical and genetic data, without presenting new clinical results.
This study suggests that individuals with severe sickle cell disease, indicated by higher hemoglobin S and ferritin levels, may have lower cortisol levels as shown by reduced hair cortisol content.
This study found low concordance between distal and proximal hair cortisol concentrations during early pregnancy, particularly when measured with different assay methods.
44 citations
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February 2016 in “Zoology” This study observed that hair cortisol concentrations in primates are influenced by factors such as age, sex, hair growth rates, and sampling methods, which must be accounted for in research designs.
24 citations
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October 2018 in “Addiction Biology” This study found that alcohol dependence is associated with altered HPA axis functioning, with AD patients showing higher hair cortisol concentrations and reduced ACTH and cortisol levels, irrespective of childhood maltreatment history.
22 citations
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August 2016 in “European Eating Disorders Review” This study found that female patients with anorexia nervosa had lower hair cortisol concentration compared to healthy and psychiatric controls, which may be influenced by body mass index rather than anorexia-related endocrine changes.
March 2026 in “Journal of Pain” Preoperative stress markers alone don't predict chronic post-surgical pain.
January 2026 in “Phaidra - Repository of the University of Veterinary Medicine, Vienna” In this study, researchers assessed cortisol levels in wolves by comparing hair and fecal samples and found a significant correlation, indicating that hair cortisol accurately reflects systemic levels, but season and body region affect results.
85 citations
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January 2014 in “Hormone Research in Paediatrics” This study found that hair cortisol concentrations can be reliably measured in healthy children and generally increase with age, unaffected by gender, puberty, or hair care practices.
76 citations
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October 2011 in “Clinica Chimica Acta” In this study, ultraviolet irradiation and immersion in shampoo and hot water significantly reduced hair cortisol, illustrating a two-stage process of cortisol loss that may impact chronic stress assessment.
50 citations
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July 2018 in “Psychoneuroendocrinology” In this study, researchers found that tritiated cortisol was incorporated into the hair of rhesus monkeys primarily as cortisol and cortisone, as well as other metabolites, after systemic administration.
33 citations
,
January 2017 in “Conservation physiology” This study found that measuring reproductive hormone levels in brown bear hair may effectively support non-invasive genetic sampling, though larger samples or more sensitive techniques are needed for broader application.
22 citations
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May 2019 in “Animals” In this study, researchers found that high hair cortisol levels, indicating stress in cows, were associated with certain shelter and cow-level conditions such as unclean environments and physical injuries.
21 citations
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January 2017 in “MethodsX” This study found that methanol is more effective than isopropanol at removing external cortisol from grizzly bear hair and suggests that the choice of solvent can influence hair cortisol concentration results.
12 citations
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December 2020 in “Comprehensive psychoneuroendocrinology” This study found that progesterone levels were higher and increased significantly throughout pregnancy, contrasting with stable levels in non-pregnant women.
7 citations
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April 2022 in “Journal of pharmaceutical and biomedical analysis” This study describes a new method using high-resolution mass spectrometry for analyzing multiple steroids in human scalp hair, with newborn hair showing the highest steroid concentrations among examined age groups.
December 2025 in “Biology Bulletin Reviews” This research review highlights how hair cortisol concentration can reflect the activation of the stress-response system in farm, domestic, and wild animals, noting it correlates with factors like species, sex, age, and environmental conditions, which may influence stress and adaptation.
May 2024 in “Journal of clinical case studies reviews & reports” This case report detailed a unique instance of hypopituitarism in a 65-year-old male presenting with symptoms including nausea, vomiting, and fatigue, attributed to secondary adrenal insufficiency, which improved following appropriate cortisol treatment.
This study reports that hair samples can be used to track chronic hormone levels, revealing stress, reproductive, and sodium regulation patterns in wildebeest related to environmental factors.
7 citations
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October 2015 in “American Journal of Primatology” The researchers observed that pregnancy in rhesus monkeys was associated with an increased incidence of hair loss, though the underlying reasons remain unclear.
This paper discusses advancements in forensic hair analysis, emphasizing a novel DART–HRMS method that improves the accuracy and efficiency of detecting drug use timelines.
January 2014 in “S. Karger AG eBooks” Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.
375 citations
,
July 2006 in “Journal of Investigative Dermatology” This review discusses the brain-skin connection, the skin's role in stress response, and highlights unmet challenges in understanding stress-induced skin inflammation but reports no new experimental findings.
374 citations
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May 2016 in “The Lancet. Diabetes & endocrinology” This article reviews the clinical complications and increased mortality risks associated with Cushing's syndrome but does not present new clinical data; it emphasizes the need for prompt treatment to mitigate these risks.
183 citations
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March 1982 in “JAMA” This study reported that spironolactone at 200 mg/day significantly improved facial hair growth in women with hirsutism and showed a sustained reduction in ovarian androgens over one year.
146 citations
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December 2016 in “Translational Andrology and Urology” This review discusses the creation of transgender-specific guidelines by WPATH and the Endocrine Society, based mostly on clinical experience, and reports no new results.
105 citations
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February 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.
77 citations
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March 2021 in “Nature” In this study, increased corticosterone from chronic stress prolonged hair follicle stem cell quiescence in mice, inhibiting regeneration, but restoring Gas6 expression overcame this inhibition.
74 citations
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March 2006 in “Journal of Chromatography B” This review discusses the use of hair analysis for detecting misuse of drugs in livestock, covering hair biology, drug incorporation, sampling methods, and analytical techniques, but reports no new findings.
69 citations
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January 2020 in “Veterinary World” This review examines factors influencing dermatophyte infection in companion animals, focusing on prevalence, clinical signs, pathogenesis, immune response, and the impact of cortisol and cytokines, but reports no new clinical results.