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This review suggests that skin may largely protect itself from CYP-generated reactive metabolites due to higher conjugating enzyme activities, while highlighting limitations in modeling human skin metabolism experimentally.

This study found that untargeted hair metabolomics analysis detected significantly altered endogenous biomolecules, potentially serving as biomarkers for identifying oxidative cosmetic hair treatments like bleaching.

Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.

This article reviews the endocrine changes in anorexia nervosa and bulimia nervosa, highlighting hypoleptinemia as a potential mediator, but does not present any new clinical results.

This study applied a machine learning-based genomic analysis to identify genetic markers associated with wool traits in Central Anatolian Merino sheep, successfully highlighting loci relevant to fiber diameter, staple length, and greasy fleece yield, which could inform breeding programs to enhance wool quality and yield.

This study found that older beef feedlot steers had higher hair cortisol concentrations, but liver abscess presence was not linked to stress-related parameters in feedlot cattle.

This study found that metabolite levels in hair samples differ significantly by hair color and segment, leading to recommendations for best practices in hair metabolomic studies.

This study developed and validated a method for measuring stress biomarkers in hair during pregnancy, finding that glucocorticoid levels increased over trimesters while endocannabinoid levels remained constant, suggesting hair analysis as a reliable tool for monitoring stress responses in pregnant women.

This study found that among young adults, willingness to provide hair and fingernail samples for cortisol measurement was similar, with discomfort around sampling as the main barrier; informational videos did not significantly alter participant willingness.

This case study describes a 36-year-old woman with a history of recurrent limb weakness linked to hypokalemia and later diagnosed with Cushing syndrome indicated by elevated cortisol levels and a pituitary mass, which was treated with surgery and radiosurgery.

This study found that current clinical, microscopic, and laboratory analyses did not reliably distinguish Alaskan malamutes with coat funk from normal dogs, indicating more research with larger samples is needed.

In this study, occasional attendance at religious services among adolescents was associated with lower hair cortisol levels, indicating lower chronic physiological stress, compared to regular attendance or none at all.

In this exploratory cross-sectional study, the researchers found a strong positive correlation between hair cortisol concentration and physical activity in patients with diastolic heart failure, but no correlation for other heart failure subgroups; perceived stress showed minimal association with physical activity across all subgroups.

This review discusses clinical, hormonal, and genetic aspects of nonclassic adrenal hyperplasia and reports no new findings; the condition is highlighted as a potential cause of premature adrenarche and other symptoms in young people.

The T-zone on the face has more androgen receptors and produces more oil than the U-zone.

This study reported that in embryo transfer cycles for women with nonclassic 21-hydroxylase deficiency, dexamethasone use was associated with improved pregnancy rates, and maintaining a BMI below 23.36 kg/m² increased pregnancy probabilities.

This study identifies a polygenic basis for atypical recurrent flank alopecia in Cesky Fousek dogs through genome-wide association analysis and gene expression profiling, highlighting several metabolic pathways involved in the condition.

This review discusses genetic and epigenetic studies of PCOS, highlighting Genome-Wide Association Studies that found genetic variants related to gonadotrophin secretion influencing PCOS susceptibility, but it reports no new findings.

A woman's hyperandrogenism was caused by a genetic mutation leading to non-classic adrenogenital syndrome.

This study found that higher dihydrotestosterone (DHT) levels are associated with reduced crowing complexity in Kokok Balenggek roosters.

The researchers reported a case of falsely elevated testosterone in a teen, due to immunoassay interference, demonstrating that liquid chromatography tandem-mass spectrometry provides more accurate testosterone measurement, emphasizing the need for thorough analysis when clinical results are inconsistent.

This review discusses female hyperandrogenism, detailing diagnostic criteria and treatment options without reporting new study results; it emphasizes improving health and quality of life for affected women.

This review discusses advances in forensic DNA profiling, highlighting new genetic markers and methods for identifying unknown individuals, but reports no new research findings.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

This review discusses the adverse effects of 5α-reductase inhibitors, finasteride and dutasteride, on sexual, psychological, and vascular health, emphasizing the need for physicians to inform patients of these risks.

This study identified the presence of apoptotic or necrotic keratinocytes and hair shaft dystrophy as potential markers of hair loss in patients with HIV-1 infection.

This study found that alopecia in captive Rhesus macaques may be linked to chronic hypersensitivity dermatitis with CD4+ cell inflammation, possibly influenced by altered housing and reduced pathogen exposure.

This study reports that a German Shepherd developed generalized calcinosis cutis following a presumed bacterial infection, representing the first known case linked to such an infection in adult dogs.

This study found that while GPT-4 shows high accuracy and efficiency in clinical decision making, physicians' critical thinking and lifelong learning skills remain essential, particularly in addressing and interpreting AI errors in medical settings.

This study found that progesterone levels were suppressed in underweight anorexia nervosa patients compared to healthy controls, as measured through hair analysis, and did not increase during short-term weight restoration.