26 citations
,
March 1995 in “Differentiation” This study isolated and sequenced the complete gene rKAP4L1, which encodes a cysteine-rich hair keratin-associated protein in rabbit hair follicles.
24 citations
,
January 1969 in “Archives of Dermatological Research” Hair malformations may occur due to timing issues in hair development.
20 citations
,
December 2012 in “Journal of molecular structure” This study found that at pH 9.0, CYS penetrated less and caused less damage to virgin human hair than TG because it barely reached the cortex region.
19 citations
,
May 2008 in “Applied spectroscopy” This study found that human hair cuticle and cortex have different protein structures, with beta-sheet and disorder configurations in the cuticle and alpha-helical structures in the cortex.
19 citations
,
July 1964 in “PubMed” This study observed that undifferentiated matrix cells at the base of the hair follicle differentiate into the medulla, cortex, cuticle, and inner root sheath cell types through specific morphological changes.
18 citations
,
August 2014 in “Lipids” This study found that unsaturated fatty acids are more abundant in the cortex of human hair than on its surface, and steryl glycoside-like lipids may help bind the cuticle to the cortex.
18 citations
,
August 2009 in “Skin Research and Technology” In this study, optical coherence tomography was used to produce 3D images of human hair, revealing that after chemical treatment with ammonium thioglycolate, the main hair structures were not identifiable due to damage.
18 citations
,
March 2009 in “Skin pharmacology and physiology” This study found that sunlight exposure causes significant structural and chemical damage to hair, including cuticle loss, cortex damage, and discoloration, with water playing a major role in discoloration of brown hair.
17 citations
,
June 2012 in “Journal of experimental zoology. Part B, Molecular and developmental evolution” This review explores theories on the evolution of hair from synapsid scales and glands, proposing mechanisms supported by comparative studies, but reports no new experimental findings.
15 citations
,
August 2020 in “Analytical chemistry” This study observed that lipids in human hair accumulate in specific areas and do not significantly impact water permeability, highlighting the utility of AFMIR for studying complex biomaterials.
15 citations
,
May 2010 in “International Journal of Cosmetic Science” This review discusses new developments in understanding the structure and properties of keratin fiber cell membrane complexes, without reporting new experimental results.
15 citations
,
February 1999 in “The anatomical record” This study found that defective cross-linking in hair cuticles is observable in a minority of mouse hair mutants, suggesting different proteins are involved in cross-linking across cell types.
14 citations
,
December 2016 in “PloS one” This study found that Keratin 26 is expressed differently in hair follicle phases, particularly during catagen and telogen, influencing cashmere growth and interacting antagonistically with the BMP signaling pathway.
12 citations
,
February 2019 in “Skin research and technology” This study found that white hair fibers have lower lipid content and different water absorption dynamics compared to brown hair fibers, suggesting differences in their barrier functions.
11 citations
,
January 2000 in “Journal of cosmetic science” This study found that hydrolyzed wheat proteins extensively penetrated both untreated and chemically treated hair, primarily occupying areas like the endocuticle and cortex.
10 citations
,
January 2012 in “Journal of biomedical optics” This study used ultrahigh-resolution optical coherence tomography to observe hair shaft structures, finding melanin granules absent only in white hair, which may explain color differences between black and white hair.
10 citations
,
January 2002 in “Nihon Keshouhin Gijutsushakaishi/Journal of S C C./Nihon Keshouhin Gijutsushakai kaishi” This study found that the cuticle layer of hair contributes approximately 60% to bending stress, highlighting its significant role in the mechanical properties of hair stiffness.
10 citations
,
December 2001 in “PubMed” This research suggests that both proposed pathways into hair fibers for molecule penetration are valid and complementary, with all fiber structures acting as potential routes for delivering materials.
9 citations
,
February 2016 in “Anatomical Science International” Hair proteins change location and structure as hair cells mature.
9 citations
,
March 2005 in “International Journal of Cosmetic Science” This study found that torsional measurements can effectively distinguish the effects of hair care products on the cuticle versus the cortex of hair fibers, unlike tensile measurements.
9 citations
,
January 2003 This article explores the structure of mammal body hair and the challenges in explaining its evolutionary origins, reporting no new empirical findings.
8 citations
,
February 2022 in “International Journal of Dermatology” This review discusses the lipid composition of human hair across ethnic types, effects of damage on lipid content, and associated changes with diseases, but reports no new findings; further research is needed.
8 citations
,
January 2016 in “Journal of fiber science and technology” This study found that cysteic acid generation during hair bleaching is diffusion-controlled, increasing with the square root of bleaching time, in both cuticles and cortex of human hair fibers.
7 citations
,
March 2003 in “Journal de Physique IV (Proceedings)” This study identified two types of calcium in human scalp hair shafts: easily removable calcium, likely as calcium soaps, and more stably bound calcium, possibly related to Ca-binding proteins.
7 citations
,
January 1995 This study found that using a high-viscosity, high-amine-content silicone fluid as a pretreatment can protect hair from bleaching and dyeing damage without affecting these processes.
6 citations
,
January 2005 in “Han-guk hyeonmigyeong hakoeji/Applied microscopy” This study found that the 16th-century mummified hair from a female mummy in Paju was remarkably well-preserved, with the hair's ultrastructural features maintained likely due to a calcium-rich surface coat.
6 citations
,
November 1984 in “Acta Dermato Venereologica” This study investigated the immunohistochemical characteristics of keratin proteins in epidermal appendages, finding variable staining patterns in different skin structures and tumor cells, which suggests differences in keratinization.
6 citations
,
June 1976 in “Journal of ultrastructure research” This study identified the presence of recognizable organelles, such as lysosomes and mitochondria, in both the keratinized fiber and the hardened inner root sheath of the Romney wool follicle.
6 citations
,
October 2003 in “Journal of applied polymer science” This study found that using poly(ethylene imine) as a counterion reagent improved the colorability and shampoo fastness of bleached human hair when dyed with an acid dye.
6 citations
,
January 1985 in “ACTA HISTOCHEMICA ET CYTOCHEMICA” This study found that epithelial components of calcifying epithelioma of Malherbe showed lectin binding and keratin staining patterns similar to normal hair follicles, with prominent Con A staining in tumor giant cells.