18 citations
,
July 2001 in “Australian veterinary journal” This case study describes a cat with concurrent cutaneous xanthomas, demodicosis, and dermatophytosis, which suggests potential primary hyperlipidaemia as the underlying cause for its symptoms.
2 citations
,
January 2017 in “Journal of veterinary emergency and critical care” This case report describes the successful management of a chemical burn on a dog's face and corneas from bleach exposure, resulting in complete lesion resolution without long-term effects.
February 2010 in “Journal of The American Academy of Dermatology” Surgery on a baby with a skin disorder improved eyelid position and eye health.
3 citations
,
June 2025 in “Gyemyeong uidae haksulji” This review suggests that PDRN shows promise as a safe and versatile regenerative agent for wound healing and other dermatological applications, based on its dual mechanisms and clinical evidence of efficacy.
April 2018 in “Journal of Investigative Dermatology” This study found that Basonuclin 1 knockdown in human primary keratinocytes significantly reduces cell proliferation and affects migration, indicating its role in coordinating the re-epithelization phase of wound healing.
1 citations
,
January 2025 in “Veterinary Medicine International” This review found promising benefits of platelet-rich plasma for treating ocular surface diseases in animals, but methodological flaws currently preclude recommending it as standard care.
May 2026 in “ACTA SCIENTIAE VETERINARIAE” This study reports a case of hepatogenic photosensitization in a 22-day-old lactating Tabapuã calf, induced by toxins ingested via breast milk from a mother fed Brachiaria decumbens pasture; treatment including pasture removal and medicinal intervention led to symptom remission.
October 2010 in “eCommons (Cornell University)” This case report highlights that cutaneous epitheliotropic lymphoma in dogs can present with various skin lesions, such as depigmentation, making diagnosis challenging for veterinarians.
73 citations
,
April 2013 in “Stem cells” This study found that LGR5 is uniquely expressed in human corneal endothelial cells and maintains endothelial cell phenotypes while inhibiting mesenchymal transformation through the Wnt pathway.
15 citations
,
August 2020 in “American Journal of Pathology” This study found that insulin promotes corneal epithelial wound healing and nerve recovery in diabetic mice through Wnt signaling, suggesting its potential as a protective factor for diabetic corneal damage.
January 2025 in “Open Life Sciences” This study observed that transgenic mice with overexpression of HE4 developed keratitis and severe corneal opacity, suggesting that HE4 may significantly influence keratopathy and inflammatory responses in the eye.
5 citations
,
October 2023 in “Aging” This study found that activating SHH signaling in EPCs enhances angiogenesis to aid in healing pressure ulcers through the PI3K/AKT/eNOS pathway, indicating SHH signaling as a potential target for treatment.
9 citations
,
September 2021 in “Stem Cell Reviews and Reports” This study concluded that hair-derived stem cells from older donors may offer a promising alternative for autologous corneal endothelial replacement, potentially benefitting patients of various age groups.
94 citations
,
January 2007 in “Cutaneous and Ocular Toxicology” This review discusses the long-term cutaneous and ocular complications from sulfur mustard exposure in the Iranian population, identifying pruritus and malignant changes as significant issues and highlighting eye surface damage leading to visual decline.
February 2010 in “Journal of The American Academy of Dermatology” A woman's nail separation was likely caused by poor blood flow, and a treatment for similar conditions might help.
87 citations
,
July 2007 in “British Journal Of Nutrition” In this study, oral administration of Lactococcus lactis strain H61 to senescence-accelerated mice was linked to reduced bone density loss, less skin ulcer incidence, and reduced hair loss, along with altered immune responses.
80 citations
,
April 2017 in “Frontiers in Pharmacology” This review examines experimental and clinical evidence on PDRN, a drug derived from salmon DNA that acts via the adenosine A2A receptor and shows promise for tissue repair and treatment of diabetic foot ulcers in regenerative medicine.
28 citations
,
January 2016 in “Vitamins and hormones” This source reports that thymosin beta 4 accelerated dermal wound repair in phase 2 clinical trials for pressure ulcers, stasis ulcers, and epidermolysis bullosa wounds and was well tolerated.
25 citations
,
October 2007 in “Developmental biology” In this study, transgenic mice altered to express a Clim-inhibiting molecule under a keratin promoter showed corneal degradation and hair follicle failure, highlighting Clim proteins' role in maintaining these tissues.
5 citations
,
October 2025 in “International Journal of Nanomedicine” This review discusses the role of traditional Chinese medicine and bioactive materials in chronic wound healing and reports no new clinical results.
4 citations
,
January 2021 in “Dermatology Review” This review discusses the role of Demodex mites in ocular demodecosis and various eye ailments, highlighting diagnostic methods but noting a lack of standardized treatments, with no new clinical results reported.
2 citations
,
September 2023 in “Curēus” This study reported that topical spironolactone improved lid margin vascularity, corneal fluorescein staining, and disease severity scores in patients with ocular graft-versus-host disease, suggesting a potential therapeutic role by enhancing corneal lipid production with minimal adverse effects.
2 citations
,
October 2016 This article discusses the range of skin-related side effects caused by chemotherapy and radiotherapy, including novel patterns emerging with targeted therapies, but does not report new clinical results.
1 citations
,
April 2024 in “Journal of Clinical Medicine” This study found that patients with severe alopecia areata demonstrated reduced corneal sensitivity and increased corneal staining, and exhibited altered topographic and biomechanical eye parameters compared to controls, suggesting a possible increased risk of keratoconus and the necessity for regular ophthalmological exams.
January 2023 in “Malaysian Journal of Medical Research” This case report describes a 7-year-old girl whose allergic conjunctivitis went underdiagnosed and undertreated, resulting in poor prognosis due to the challenges associated with her young age and inability to verbally communicate symptoms.
2 citations
,
April 2022 in “PubVet” This case report discusses a 5-year-old Persian cat with feline eosinophilic granuloma complex, which responded positively to prednisone and topical corticosteroids, eliminating itching and promoting fur regrowth without relapse.
1 citations
,
February 2021 in “Gastroenterology” This report discusses a case of vesiculopustular eruption in a patient with ulcerative colitis, highlighting the effective use of ustekinumab for treatment and suggesting its consideration in similar cases of IBD-related skin lesions.
14 citations
,
May 2022 in “International Journal of Molecular Sciences” This study found that platelet-rich plasma therapy reduced inflammation and improved bladder function in a rat model of ketamine-induced ulcerative cystitis.
4 citations
,
January 1992 in “American Journal of Ophthalmology”
165 citations
,
June 2007 in “European Journal of Cell Biology” This review discusses the various stem cell populations associated with hair follicles and their potential in regenerative medicine, highlighting differences between murine and human hair follicles but reports no new clinical results.