3 citations
,
December 2019 in “Biomaterials Research/Biomaterials research” This study found that the concentrations of major inorganic elements in human scalp hair increase with age up to 25 years, and calcium and magnesium concentrations are significantly associated with sex in individuals over 20.
2 citations
,
July 2024 in “Skin Research and Technology” Copper may protect against alopecia areata, while certain inflammatory markers increase risk.
2 citations
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June 2016 in “Russian Journal of Skin and Venereal Diseases” This study reported a decrease in zinc and iron levels in the blood and an increase in certain trace elements in hair among patients with alopecia areata compared to healthy individuals.
2 citations
,
July 1998 in “Dermatologic Clinics” This review examines the differences in dermatology practices between Europe and North America, noting that European dermatologists often prioritize evaluating patients' psychosocial factors and utilize nondrug treatments, unlike their North American counterparts.
2 citations
,
June 1986 in “Journal of Clinical Pharmacy and Therapeutics” This study demonstrated that certain metal salts can bind to sodium valproate and discussed the potential link to hair loss in patients treated for epilepsy.
2 citations
,
January 1976 in “Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)” This study found that sodium and potassium levels in scalp hair might be sex-specific indicators, while females had slightly higher copper and iron levels, particularly during the reproductive period.
2 citations
,
November 2023 in “Bioactive materials” The researchers reported that a newly developed ionic liquid-based microemulsion significantly improved the local delivery of copper peptides in mice, enhancing hair growth-related factor activation while offering a safer, non-invasive alternative to existing treatments for hair loss.
2 citations
,
March 2023 in “Frontiers in Bioengineering and Biotechnology” This study found that CuO/SiO2 nanowires enhanced with photothermal therapy exhibit significant antibacterial effects against E. coli and S. aureus and promote wound healing and vascularization, suggesting potential as an alternative treatment for infected wounds in mouse models.
2 citations
,
February 2023 in “International journal of molecular sciences” This study identified that copper depletion in dermal papilla cells reduced hair growth by boosting ROS levels, but ROS scavengers like NAC and ascorbic acid partially alleviated this effect.
2 citations
,
October 2018 in “The journal of pediatrics/The Journal of pediatrics” This case report identified a 4-month-old boy with Menkes disease, a neurodegenerative disorder of copper metabolism, noting symptoms like recurrent seizures, developmental delay, and specific physical characteristics, confirmed by genetic sequencing showing a pathogenic ATP7A mutation and low serum copper and ceruloplasmin levels.
2 citations
,
January 1987 in “Acta Agriculturae Scandinavica” This study found that subcutaneous injections of certain chelators led to skin and hair depigmentation, increased skin elasticity, and disturbed hair growth in minks, without affecting fur quality.
1 citations
,
November 2023 in “Frontiers in veterinary science” Goat hair shows changes in metal levels and stress when goats move from indoors to mountain pastures.
1 citations
,
January 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This review examines the role of trace elements like zinc, selenium, and copper in treating alopecia and discusses the mechanisms by which their imbalance affects hair loss, but reports no new clinical findings.
1 citations
,
June 2022 in “Movement disorders clinical practice” This study reports a unique case of trichotillomania as a presenting sign in a patient with neurological Wilson's disease, confirmed by genetic testing and copper abnormalities.
1 citations
,
June 2022 in “Zagazig Veterinary Journal/Zagazig Veterinary Journal (Online)” This study found that mange was the most common cause of alopecia in dogs, with cases being more prevalent during the summer and among dogs less than one year old.
1 citations
,
January 2017 in “Annals of dermatology/Annals of Dermatology” Mineral levels in hair don't significantly affect the severity of atopic dermatitis in children.
1 citations
,
December 2015 in “Lʹvìvsʹkij klìnìčnij vìsnik” This review discusses the connection between alopecia areata and trace element imbalances, noting deficiencies in elements like zinc and selenium, but reports no new clinical findings.
1 citations
,
January 2014 in “Assiut Veterinary Medical Journal/Maǧallaẗ Asyūṭ al-ṭibiyyaẗ al-baytariyyaẗ” This study in Aswan governorate reported that emaciated cattle showed decreased blood cell counts and serum minerals, as well as elevated liver enzymes, possibly associated with parasitic infections.
1 citations
,
August 2012 in “Journal of Emerging Trends in Engineering and Applied Sciences” This study found that smoking may lead to earlier onset of androgenetic alopecia in Nigerian subjects, potentially mediated by alterations in serum trace elements.
1 citations
,
July 2012 in “EFSA journal” This report concludes that no cause and effect relationship has been established between consuming KF2BL20 and maintaining normal hair in healthy adults.
1 citations
,
November 2011 in “Dermatologica Sinica” This study found a significant decline in serum zinc levels among women of African descent using hair relaxers and experiencing alopecia, with age at first exposure potentially influencing alopecia development.
1 citations
,
August 2011 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that women with lower hair loss six months after bariatric surgery consumed more zinc and iron and showed less compromise in the nutritional status of these minerals compared to women with more significant hair loss.
1 citations
,
September 2008 in “International Journal of Cosmetic Science” This study demonstrated that using chelants like N , N ′ ‐ethylenediamine disuccinic acid in hair coloring products can significantly reduce keratin fiber damage by preventing the formation of metal-induced free radicals.
1 citations
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June 2007 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” This study found that a two-month antioxidant treatment significantly improved hair growth in patients with alopecia areata by enhancing antioxidant defenses and correcting trace metal imbalances.
1 citations
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December 2023 in “Nanomaterials” In this study, the researchers synthesized copper-doped mesoporous silica nanoparticles and observed that they enhance tumor microenvironment regulation and, when paired with disulfiram, effectively kill cancer cells while also showing synergistic anti-tumor effects with immune checkpoint inhibitors.
1 citations
,
November 2019 in “Damanhour Journal of Veterinary Sciences” This study observed that mixed breed cows with alopecia, ill-thrift, and infertility had significant decreases in serum copper, zinc, calcium, inorganic phosphorus, and magnesium, alongside signs of anemia.
1 citations
,
May 2016 in “Marmara Pharmaceutical Journal” This study determined the stability constants of finasteride complexes with cobalt, zinc, cadmium, and copper, which may inform analyses of blood samples.
1 citations
,
June 2013 in “Semina Ciências Agrárias” This study found that although soil and forage in Middle Paraíba, Brazil, contained normal to high copper levels, the surrounding bovine populations showed signs of copper deficiency likely due to antagonistic effects from high iron, zinc, and manganese levels.
September 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this paper, the authors propose that a historical decline in dietary tin intake may contribute to cardiovascular issues and accelerate pattern hair loss by causing copper and zinc depletion, which impairs heart function and scalp circulation.
September 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this paper, the authors propose that a major reduction in dietary tin over the past century could be linked to increased cardiovascular issues and androgenetic alopecia, hypothesizing that tin deficiency disrupts heart function and scalp circulation by depleting copper and zinc.