3 citations,
July 2017 in “Journal of Molecular Graphics & Modelling” The study found that baicalin has different stable shapes in gas and water, with two shapes better for interacting with positive charges in water.
13 citations,
September 2017 in “International Journal of Cosmetic Science” Thioglycerol treatment at pH 9.0 with ammonia causes less hair damage and better waving than thioglycolic acid.
10 citations,
September 2022 in “Animals” Certain genes affect udder shape in Holstein cows, important for health and milk production.
Yak hair stretches mainly due to macromolecules slipping past each other.
7 citations,
May 2015 in “Journal of biological chemistry/The Journal of biological chemistry” Different ligands change the shape of the TRPV3 ion channel in unique ways.
28 citations,
September 2021 in “EMBO reports” Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
13 citations,
February 2015 in “Journal of Pharmaceutical Sciences” Three finasteride forms exist; "form X" doesn't.
64 citations,
July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
42 citations,
January 2005 in “Applied spectroscopy” Hair from breast cancer patients shows changes in structure and composition, and a test using these changes detected cancer but also falsely identified some healthy samples as cancerous.
4 citations,
August 2014 in “Journal of molecular structure” Chemical treatments on bleached black hair change its internal structure by breaking and reforming bonds, and treatments with hydrolyzed eggwhite protein help repair it.
December 1998 in “Acta Crystallographica Section C-crystal Structure Communications” A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.
February 2018 in “Biophysical Journal” Cyclosporine A slowly changes cell membranes, explaining some of its effects and side effects.
36 citations,
March 2005 in “Biotechnology and Bioengineering” A new method speeds up insulin amyloid fibril growth, useful for studying diseases.
28 citations,
September 2000 in “Journal of Medicinal Chemistry” Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.
23 citations,
June 2014 in “International Journal of Cosmetic Science” Glyoxylic acid is a safer alternative to formaldehyde for hair straightening and effectively changes hair structure.
20 citations,
March 2013 in “Journal of Lipid Research” The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.
12 citations,
January 1998 in “Endocrine journal” Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
6 citations,
November 2017 in “Scientific reports” The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.
4 citations,
July 2020 in “Research Square (Research Square)” The research helps understand how finasteride works and aids drug development.
1 citations,
February 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.
January 2024 in “International Journal of Cosmetic Science” A new method using 1,4-n-butylene dimaleate effectively repairs and strengthens damaged hair.
The research found how certain drugs and polymers form stable complexes, which could help develop new pharmaceutical forms.
October 2023 in “Journal of Molecular Liquids” A new method using imidazole-based liquids efficiently extracts keratin from yak hair.
The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
February 1999 in “Analytical Sciences” A new antiandrogen compound was made and its detailed three-dimensional shape was described.
January 2004 in “Analytical Sciences: X-ray Structure Analysis Online” The document explains how to make a compound called 3.BETA.-Benzoyloxy-4-pregnen-16.ALPHA.,17.ALPHA.-epoxy-6,20-dione and describes its crystal structure.
510 citations,
August 2006 in “Endocrinology” The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.
47 citations,
February 2014 in “Aaps Pharmscitech” Improved hair loss treatment using special particles and surfactants.
14 citations,
April 2019 in “Genes” Researchers found a genetic region that influences the number of coat layers in dogs.
1 citations,
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.