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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Hair growth is cyclic and influenced mainly by local factors.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.