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The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Minoxidil and finasteride effectively treat hair loss.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.

The document discusses various eye conditions and their treatments, including a rare eye cancer in a baby, vision loss from a cancer drug, cataracts from a baldness treatment, a rare skin disorder, and a specific type of eye disease diagnosed with a special imaging technique.

Finasteride, often used for hair loss, can potentially cause cataracts.

Different hair loss types need accurate diagnosis for proper treatment.

Multiple eye conditions were studied, highlighting the importance of various imaging methods for diagnosis, the vision side effects of drugs tamoxifen and Propecia, and the usefulness of optical coherence tomography for diagnosing and monitoring macular and retinal diseases.

Patients with acne vulgaris have lower serum irisin levels.

Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.

Researchers discovered potential origins and new treatments for skin cancer, including biomarkers for melanoma and therapies that reduce tumor growth.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Lactate production is important for activating hair growth stem cells.

The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Early and personalized treatment for hair loss in young people is crucial to prevent permanent damage and should include psychological support.

A male with aromatase deficiency improved bone health with estradiol treatment.

CD98hc's role in skin health decreases with age.

Diagnose and manage CCCA with thorough history, exams, and labs; treat with anti-inflammatory agents, stress reduction, and stopping harmful hair practices.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

FoxN1 gene is essential for proper thymus structure and preventing hair loss.