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Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Men with enlarged prostates often have more severe baldness.

Keratins are important for skin cell health and their problems can cause diseases.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Different harmful mutations in the CDH3 gene cause HJMD, but symptoms vary among individuals.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.

Wnt10b helps blood stem cells grow after injury.

Spironolactone helps reduce pain and lesions in hidradenitis suppurativa patients, and lower doses are also effective.

Valproic acid may help hair grow and could be a safe treatment for hair loss.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Premature graying of hair may suggest health issues and currently lacks effective treatments.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Researchers developed a new type of memory using antiferromagnets that is stable, not disrupted by magnets, and works at room temperature.

New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.