research Roles of Hippo signaling pathway in size control of organ regeneration
This article introduces the concept of organ size control in regeneration, regulated by the Hippo signaling pathway, but reports no new experimental results.
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60-90 / 1000+ resultsresearch Cloning of human, murine, and marsupial keratin 7 and a survey of K7 expression in the mouse
This study reports that K7 expression patterns observed in mice are similar to those in humans, revealing previously unreported expression in the gastrointestinal tract, tongue, and various "hard" epithelial tissues.
research Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea
This study found that coactivating LIN28B and follistatin enhances cochlear supporting cells' ability to regenerate hair cells in neonatal mice by reprogramming them into progenitor-like cells.
research Recent advances in the characterization of hair of mummies from the Chilean Andean coast
This study found that two pre-Hispanic mummies from the Andean coast had well-preserved hair with significant amounts of heavy metals like iron, lead, bromide, and occasionally arsenic, revealing their historical context.
research Chromosomal localization of acidic and basic keratin genes of the domestic dog
This study reports that the acidic and basic keratin gene clusters in dogs are located on chromosomes CFA9 and CFA27, respectively, similar to genetic arrangements in humans and mice.
research Expression of the β-Catenin Gene in the Skin of Embryonic Geese During Feather Bud Development
In this study, beta-catenin expression was found to be significant in embryonic goose skin during early feather bud development, with patterns similar to Shh expression, suggesting its importance in normal development.
research Low Heterozygosity and Historical Bottleneck Effect Depicted From the Genome Assembly of the Indus River Dolphin (Platanista minor)
This study reports the draft genome sequence of the endangered Indus River dolphin and suggests potential genetic adaptations to freshwater environments, including specialized skin features and immune adaptations, while also highlighting historical and human-induced factors contributing to its low genetic diversity.
research Segmental hair analysis as a retrospective testosterone diary: possibilities and pitfalls
This study observed that testosterone concentrations in hair segments show some stability over time, but are influenced by factors like sebum integration, hair washing frequency, and individual hair growth rates.
research VIJAYA-The one who fights to win
This narrative from Vijaya, a breast cancer patient, shares her personal experience with diagnosis, treatment, and support, highlighting the importance of emotional resilience and support groups.
research Identificação e cultivo de células somáticas do folículo das penas como fonte para banco de recursos biológicos de espécies de aves selvagens
The study focused on the identification and cultivation of somatic cells from feather follicles as a source for a biological resource bank for wild bird species. The research aimed to establish a method for preserving genetic material from these species, which could be crucial for conservation efforts. By successfully isolating and cultivating these cells, the study provided a potential tool for maintaining biodiversity and supporting the conservation of avian species. This approach offered a novel way to create a repository of genetic resources that could be used for future research and conservation initiatives.
research Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations
This study identified at least four distinct fibroblast populations in adult human skin, each with unique functional properties, suggesting potential therapeutic applications for wound healing and fibrosis-related diseases.
research Research on Medicinal Plants and Traditional Medicine in Africa
Traditional African medicinal plants should be scientifically tested and integrated into modern healthcare.
research Expression of Hypothalamic–Pituitary–Thyroid Axis RelatedGenes in the Human Skin
This study found that thyroid-stimulating hormone receptors are functionally expressed in various skin cells, implying potential physiological and pathological roles in skin, especially in conditions like autoimmune diseases.
research Integrated analysis of coding genes and non-coding RNAs during hair follicle cycle of cashmere goat (Capra hircus)
This study identified potential ceRNA regulatory networks in cashmere goat hair follicle cycling, expanding understanding of lncRNA and miRNA biology and annotation of the goat genome.
research Extraction and Analysis of Cortisol from Human and Monkey Hair
This study validated a method for measuring cortisol levels in hair, which may serve as a biomarker for chronic stress in both humans and various animals.
research Annotation of sheep keratin intermediate filament genes and their patterns of expression
In this study, researchers identified nine new sheep keratin genes, highlighting species-specific differences in the expression and compartmentalization of wool-related keratin genes compared to humans.
research Towards the validation of endogenous steroid testing in wildlife hair
This review discusses the use of hair analysis for examining stress and reproduction hormone levels in wildlife and highlights the need for more comprehensive physiological validations across species.
research Acute and Long-term Toxicity of Cyclophosphamide
This article reviews the use of cyclophosphamide in kidney disease treatment, highlighting significant concerns about long-term risks of cancer and infertility, and stress strategies for dose reduction and side effect mitigation; no new study results are presented.
research Cross-species sensitivity to a novel androgen receptor agonist of potential environmental concern, spironolactone
This study found that spironolactone reduced fish fecundity and caused masculinization of females at certain concentrations, while having no effect on Daphnia magna reproduction, underscoring concerns for environmental exposure to vertebrates.
research Isolation and Characterization of Mouse High-glycine/Tyrosine Proteins
This study found that genes encoding mouse high-glycine/tyrosine proteins show distinct spatial and temporal expression patterns in hair follicles, suggesting diverse protein distribution during hair growth cycles.
research HEALTH SURVEY OF BOREAL CARIBOU (RANGIFER TARANDUS CARIBOU) IN NORTHEASTERN BRITISH COLUMBIA, CANADA
This study found that a significant number of boreal woodland caribou in NE British Columbia showed symptoms of trace mineral deficiencies and exposure to various pathogens, with substantial winter tick infestations affecting a majority of individuals.
research Medicinal Value of Three Agricultural Weed Species of the Asteraceae Family: A Review
This review discusses the traditional uses, phytochemical, and pharmacological studies on Ageratum conyzoides, Tridax procumbens, and Bidens pilosa, emphasizing the need for further clinical research into their medicinal potential, but it does not report new results.
research An incompletely penetrant novel MAFB (p.Ser56Phe) variant in autosomal dominant multicentric carpotarsal osteolysis syndrome
This study identified a novel missense MAFB variant in a family with some unaffected members, suggesting incomplete penetrance and the potential influence of modifier genes, epigenetic mechanisms, or environmental factors on MCTO phenotype.
research Distinct tooth regeneration systems deploy a conserved battery of genes
This study found that zebrafish and sticklebacks, despite differences in their tooth regeneration structures, share a similar genetic program during tooth regeneration, suggesting a conserved "successional dental epithelium" in vertebrates.
research Structural Hierarchy of Trichocyte Keratin Intermediate Filaments
This review discusses recent advances in understanding the structural hierarchy of trichocyte keratins, including their heterodimeric structure and distinct conformations impacting hair growth, with no new experimental results reported.
research The Organizer and Beyond
This review discusses historical and recent advances in understanding the embryonic organizer's role in patterning during development, including molecular pathways and future research challenges, but reports no new experimental data.
research Mining Therapeutic Efficacy from Treasure Chest of Biodiversity and Chemodiversity: Pharmacophylogeny of Ranunculales Medicinal Plants
This review discusses the molecular phylogeny, chemical constituents, and therapeutic applications of medicinal plants in the Ranunculales order and reports no new clinical results.
research Dermatophytosis Caused by Microsporum canis in a Free-Living Maned Wolf (Chrysocyon brachyurus).
This report describes the first diagnosed case of dermatophytosis caused by Microsporum canis in a young maned wolf, emphasizing the importance of monitoring emerging diseases in this vulnerable species.
research The clock within
This study found that the circadian clock regulates the activation and heterogeneity of hair follicle bulge stem cells, affecting tissue homeostasis and tumorigenesis risk in mouse skin.
research Analysis of Genetic Diversity and Construction of a Core Collection of Ginkgo biloba Germplasm Using EST-SSR Markers
In this study, researchers assessed the genetic diversity of 101 Ginkgo biloba individuals using EST-SSR markers and concluded that there is a high level of genetic diversity in Ginkgo populations, facilitating the construction of a core germplasm collection for breeding purposes.