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New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Burn reconstruction improves with new techniques, materials, and tissue engineering.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Nearly all elderly nursing home residents had a skin disease, with dry skin being the most common.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

The CLASI is a reliable tool for measuring the severity of cutaneous lupus erythematosus.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Combination drug therapy is effective for hirsutism that doesn't improve with just one medication.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Long-term minoxidil use can cause pseudoacromegaly, but stopping it improves symptoms.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Plant-based ingredients are effective and safe for modern skincare products.

Changing Wnt signaling can lead to more or less hair growth and might help treat hair loss and skin conditions.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.