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This study found that alopecia areata patients have a higher prevalence of carotid subclinical atherosclerosis, with factors such as disease duration, systemic inflammation, and insulin resistance potentially contributing to this increased risk.

This study found that oral biotin supplementation improved outcomes in a mouse model of inflammatory bowel disease by reducing inflammatory cytokine production and enhancing intestinal barrier integrity, suggesting potential therapeutic benefits for IBD patients.

This study reported that CYP21A2 heterozygous mutations do not significantly contribute to the pathogenesis of polycystic ovary syndrome.

This article provides guidelines for molecular genetic testing of congenital adrenal hyperplasia due to 21-hydroxylase deficiency, focusing on quality requirements, methodologies, and variant classification; it reports no new clinical results.

This review discusses the pathophysiology, genetics, and management of nonclassic congenital adrenal hyperplasia, noting subfertility and hormonal issues without providing new clinical results.

This study reported that in embryo transfer cycles for women with nonclassic 21-hydroxylase deficiency, dexamethasone use was associated with improved pregnancy rates, and maintaining a BMI below 23.36 kg/m² increased pregnancy probabilities.

This review discusses clinical, hormonal, and genetic aspects of nonclassic adrenal hyperplasia and reports no new findings; the condition is highlighted as a potential cause of premature adrenarche and other symptoms in young people.

This review covers the pathophysiology, diagnosis, and treatment of nonclassic congenital adrenal hyperplasia due to P450c21, but it reports no new clinical results.

This study determined that nonclassical congenital adrenal hyperplasia has a 2.2% prevalence among hyperandrogenic women in Spain, with basal serum 17-hydroxyprogesterone showing excellent diagnostic performance.

This review discusses mammalian models of epimorphic regeneration to define a vertebrate regeneration blastema, concluding that regenerative failure likely stems from cellular responses to the microenvironment after injury, not progenitor cell availability, and calls for targeted modification studies in mammals to advance human regeneration.

This review discusses the various causes of hirsutism other than PCOS, emphasizing the importance of distinguishing potentially life-threatening conditions like androgen-secreting tumors from more benign causes; it reports no new clinical findings.

This study reports that in women with non-tumor hyperandrogenism, a decrease in serum testosterone from insulin-sensitizing therapy like metformin may indicate a low likelihood of having an androgen-secreting tumor.

This case report describes a woman with hyperandrogenism and menstrual disturbances, where an ovarian steroid cell tumor was identified and removed, leading to resolution of symptoms.

This review discusses the pathogenesis of hirsutism and related diagnostic criteria for polycystic ovary syndrome in Korean women, but reports no new clinical results.

This case report highlights a rare ovarian steroid cell tumor as the cause of androgen excess in a 36-year-old woman and underscores the importance of thorough preoperative workup to avoid unnecessary surgery.

This article reviews the clinical and biochemical features of genetic mutations affecting dihydrotestosterone production and their potential role in male pseudo-hermaphroditism, but presents no new clinical results.

This review discusses the clinical features and therapeutic goals for teenagers with PCOS, emphasizing the need for further research into its causes and potential long-term health risks, but reports no new clinical results.

This review discusses the management of hirsutism in women, highlighting promising treatments like metformin for polycystic ovarian syndrome, and emphasizes the importance of understanding hair growth cycles and realistic treatment expectations; it reports no new clinical results.

This case report describes a 6 1/2-year-old girl with significant height growth and early pubic hair development.

This review examines the causes, assessment, and treatments of hirsutism and highlights the need for future research in managing this condition but presents no new research findings.

In this study, polycystic ovary syndrome was the most prevalent cause of androgen excess, and suppressive hormonal therapy improved hirsutism, menstrual dysfunction, and acne in most patients, though side effects were common.

In this study, idiopathic hirsutism was identified as the most common cause of hirsutism among the participants, with a significant difference in hormone levels between cases of polycystic ovarian syndrome and idiopathic hirsutism.

This study concluded that heterozygosity for CYP21 mutations is associated with higher mean and free testosterone levels in women but does not significantly increase their risk of developing clinically evident hyperandrogenism.

This review discusses the broader roles of angiogenic factors, like VEGFs and FGFs, beyond angiogenesis, highlighting their involvement in various biological and pathological processes.

This review discusses the diagnostic challenges of PCOS in adolescents, noting that the persistence of hyperandrogenism and oligomenorrhea is required for diagnosis, while genetic studies suggest involvement of the hypothalamic-pituitary-ovarian axis.

This article discusses the association of acne with various systemic diseases, emphasizing the role of androgen steroids, insulin resistance, and inflammation in acne pathogenesis, but it reports no new clinical results.

This review discusses the causes, clinical features, diagnostic approach, and treatment options for hirsutism in women, but reports no new findings.

This review found that hormonal therapies, including FDA-approved combined oral contraceptive pills and spironolactone, are effective and well-tolerated treatments for acne vulgaris in adolescents with or without endocrine disorders, providing alternative options to antibiotics.

This review identifies and discusses various endocrine-related causes of hypertension in children and adolescents, emphasizing the role of genetic predispositions and highlighting the need for systematic diagnostic guidelines and genetic sequencing referrals to improve diagnosis and treatment strategies.

This study suggests that melatonin plays a role in hair follicle function by modulating growth and pigmentation, and it may act as a protective agent in active hair growth phases.