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GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

The research found that the molecule lncRNA-H19 helps hair follicle cells grow by affecting certain cell pathways in cashmere goats.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Biologics for severe asthma have known side effects, but some new risks need more study.

4-octyl itaconate may prevent hearing loss caused by the drug cisplatin by activating certain cell protection pathways.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Changing the diet of mice lacking the enzyme CBS can affect symptoms related to the genetic condition.

Non-coding RNAs play key roles in the hair growth cycle of Angora rabbits.

Retinoic acid helps change skin cells and is important for skin development and hair growth.

Teriflunomide is an effective and safe first-line oral treatment for relapsing multiple sclerosis.

New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

OsUEV1B protein is essential for controlling phosphate levels in rice.

DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Phototrichogram helps assess hair loss severity.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

Notch signaling disruptions can cause various skin diseases.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Finasteride and tamsulosin hydrochloride can be safely taken together without significant interaction.