17 citations
,
January 1997 in “Cell and Tissue Research” This study found that a serum-free DMEM-F12 medium with 45% oxygen best supports in vitro development and differentiation of human fetal skin, closely mimicking the in vivo state.
15 citations
,
October 2020 in “European journal of pharmaceutics and biopharmaceutics” This study reported that combining microdialysis and selective follicular closure with varnish significantly reduces caffeine penetration through hair follicles in an ex vivo porcine ear skin model.
14 citations
,
January 2001 in “Clinical chemistry” This article discusses the potential use of hair fibers to noninvasively measure polyamine concentrations as a marker of tumor growth, but reports no new clinical findings.
13 citations
,
December 2020 in “PLoS ONE” This study found dependencies between genetic variants and various phenotypes related to fetal and early childhood growth and neurological development in healthy infants, suggesting significant gene candidates for further investigation.
12 citations
,
April 2016 in “PLoS ONE” This study found that the Chinese version of the Polycystic Ovary Syndrome Quality of Life Questionnaire (Chi-PCOSQ) is sensitive to clinical changes and effectively assesses health-related quality of life in Chinese women with PCOS.
11 citations
,
July 2021 in “Physiologia Plantarum” In this study, the gene SlPHL1 was identified as a transcription factor in tomatoes that enhances phosphate starvation responses by upregulating specific genes.
11 citations
,
December 2018 in “Assay and Drug Development Technologies” This review highlights the challenges in screening for steroid 5 alpha-reductase inhibitors and discusses significant variability in the effectiveness of finasteride and dutasteride, calling for standardized testing methods to develop safer, more specific inhibitors from herbal preparations.
11 citations
,
April 2016 in “The American Journal of Dermatopathology” This review discusses the current knowledge on using special and immunohistochemical stains for diagnosing hair disorders, concluding that no stains are recommended for routine use in hair pathology.
11 citations
,
March 2007 in “Journal of Hypertension” This article provides contact information for Professor A. Brew Atkinson and reports no new research findings; it is not a study abstract.
11 citations
,
December 2006 in “Expert Review of Dermatology” This article examines the emerging role of dermoscopy in skin cancer diagnosis and reports no new clinical findings; the authors highlight its potential to enhance dermatological practice.
10 citations
,
December 2010 in “British Journal of Dermatology” This study reports two distinct patterns of hair changes in postmenopausal women, linking diffuse generalized scalp hair loss to older age and frontal hair loss to higher facial hair scores and younger age.
10 citations
,
January 2008 in “Biological and Pharmaceutical Bulletin” This study found that trans-3,4'-Dimethyl-3-hydroxyflavanone reduces active TGF-beta2 levels in human keratinocytes, suggesting it may enhance hair growth by suppressing the TGF-beta2 activation pathway.
9 citations
,
January 2019 in “American Journal of Dermatopathology” This study found that both androgenetic alopecia and alopecia areata showed significantly increased DKK-1 expression, potentially implicating it in the pathogenesis and as a treatment target for these conditions.
9 citations
,
August 2014 in “European journal of ophthalmology” This study found that PGF 2α receptors were predominantly present in the inner root sheath of the bulb and stem of human eyelashes during the anagen phase.
9 citations
,
August 2013 in “Middle East Fertility Society Journal” This study found that the hospital-based prevalence of polycystic ovarian syndrome among Omani women of reproductive age was 2.8%, similar to rates reported in other countries.
9 citations
,
February 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This review discusses the complexity and genetic organization of human keratin gene clusters and addresses the ongoing need for an updated unified naming system; it reports no new clinical results.
8 citations
,
January 2011 in “Organic and Biomolecular Chemistry” Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.
8 citations
,
June 2024 in “APOPTOSIS” In this review, researchers discussed recent insights into caspases, enzymes initially associated with cell death and inflammation, revealing their broader roles in cell proliferation, migration, and differentiation, and highlighting the importance of caspase knock-out mice for understanding their implications in diseases.
8 citations
,
October 2023 in “Folia Histochemica et Cytobiologica” This study observed that exosomes from adipose mesenchymal stem cells overexpressing hepatocyte growth factor significantly improved liver function and reduced fibrosis in mice with experimentally induced liver injury.
8 citations
,
January 2020 in “Skin appendage disorders” This review found that supplements containing saw palmetto may improve hair quality and density in patients with androgenetic alopecia and telogen effluvium, but more large-scale RCTs are needed for conclusive evidence.
8 citations
,
June 2019 in “Pharmaceutical research” This study found that using short durations of heat with chemical penetration enhancers improved isotretinoin delivery to human skin, especially via the hair follicles.
8 citations
,
May 2004 in “Textile Research Journal” This study reports promising preliminary results for using monoclonal antibodies to identify cashmere fibers, highlighting observed immunological differences from wool keratins.
7 citations
,
August 1989 in “The Journal of Dermatologic Surgery and Oncology” This article discusses facelift surgery, highlighting its refinement, outpatient use, low complication rates, and ease of mastery for advanced dermatologic surgeons, and reports no new clinical results.
6 citations
,
March 2021 in “Journal of Cosmetic Dermatology” In this study, platelet-rich plasma treatment improved hair regrowth and characteristics in mice and showed therapeutic efficacy in Chinese patients with androgenetic alopecia.
6 citations
,
August 2018 in “BMJ open sport and exercise medicine” This review discusses studies on resistance training for improving PCOS symptoms and reports no new results, highlighting the need to consider diet alongside exercise and calling for more research.
6 citations
,
July 2015 in “Journal of Investigative Dermatology” Chicken feather gene mutation helps understand human hair disorders.
6 citations
,
May 2014 in “Biomarkers and Genomic Medicine” This review discusses Charnoly bodies as biomarkers of cell injury and potential therapeutic targets in neurodegenerative, cardiovascular, and cancer treatments but reports no new clinical results.
6 citations
,
April 2013 in “International Journal of Dermatology” This correspondence article discusses a case of androgenetic alopecia treated with valproic acid but does not present new clinical findings.
6 citations
,
July 2007 in “Organic Process Research & Development” This study optimized the reaction conditions for the stereoselective hydrogenation of a compound used in manufacturing finasteride and dutasteride, improving the selectivity for the desired isomer.
6 citations
,
September 1990 in “International Journal of Gynecology & Obstetrics” This case report describes a rare instance of pruritic urticarial papules and plaques of pregnancy in a 25-year-old caucasian primigravida during the third trimester, discussing management recommendations.