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research Alopecia Androgenética Masculina A Importância da Continuidade Terapêutica em uma Condição Crônica Evolutiva
This study detailed a comprehensive hair therapy regimen for a 22-year-old male with androgenetic alopecia, observing significant improvements in scalp health and hair density over four months, though benefits regressed after stopping treatment, emphasizing the need for continuous adherence and multidisciplinary support.
research From geroprotective tactics to anti-ageing strategy:ways to eliminate ageing per se
This review discusses two approaches to address aging: a tactical method to delay and slow age-related issues, and a strategic method aiming to eliminate aging altogether by targeting its root cause.
research SUN-305 Hair Cortisol Measurement: An Innovative Method for Diagnosis and Follow-Up in Patients with Cushing’s Disease
This study suggests that hair cortisol measurement could serve as an alternative diagnostic method for Cushing’s disease, showing acceptable concordance with urinary free cortisol despite differing evaluated periods.
research Case Report: Multimodal contact immunotherapy in alopecia areata: long-term clinical experience in the JAK inhibitor era
This case series described five patients with chronic alopecia areata who successfully maintained long-term disease control using a combination of topical immunotherapy and other treatments over 9–15 years, highlighting the approach's continued value alongside novel therapies.
research COLLAB: A Global Survey of Clinical and Laboratory Assessment in Alopecia Areata by Hair Specialists
This study found that laboratory testing practices for alopecia areata vary among international hair experts, with the majority routinely conducting thyroid function and complete blood count tests, yet exhibiting diverse approaches toward testing for other conditions or before prescribing systemic therapy.
research MON-594 Alternating Hypothyroidism and Hyperthyroidism Complicated by Thyroid Eye Disease
In this case report, a 70-year-old woman with a history of autoimmune hypothyroidism experienced alternating hypothyroidism and hyperthyroidism over a decade, highlighting the potential role of thyrotropin receptor autoantibodies in these fluctuations.
research Steroid Responsive Mononeuritis Multiplex in the Cronkhite–Canada Syndrome
In this case report, a patient with Cronkhite-Canada syndrome also had mononeuritis multiplex, and the authors suggest that an autoimmune mechanism may be involved based on steroid responsiveness and electrophysiological findings.
research Post-Exposure Syndromes as State-Space Trapping: A set-theoretic perspective on PSSD and the post-exposure family.
This study examines how conditions like PSSD, Long COVID, and ME/CFS form a "Post-Exposure Syndromes" family, initiated by transient exposures but persisting due to complex state-space dynamics, and suggests improving pharmacovigilance to better address and understand these persistent syndromes.
research Post-tyrosinase Inhibition of Melanogenesis by Melatonin in Hair Follicles in Vitro
research 04094 Quality of care and risk of relapse in porphyria cutanea tarda: a study from the Norwegian porphyria registry
In this study, Norwegian researchers followed over 350 patients with porphyria cutanea tarda for an average of 7 years and found that 25% experienced biochemical relapse, suggesting the importance of routine follow-up for early detection and management.
research Clinically-Relevant Chemotherapy Interactions with Complementary and Alternative Medicines in Patients with Cancer
This study discusses clinically relevant interactions between anticancer drugs and herbal medicines used by cancer patients, highlighting potential herb-drug interactions and emphasizing the need for careful monitoring to minimize risks.
research Unusual Cause of Chronic Diarrhea: Cronkhite-Canada Syndrome
This case report describes a 37-year-old Filipino man with Cronkhite-Canada syndrome who improved after receiving nutritional support and medical treatment, despite the typically poor prognosis of the condition.
research Chronic stress as a trigger for telogen effluvium: a psychophysiological aspect in the practice of a trichologist
In this study, the authors explored the multifaceted connection between stress and stress-induced telogen effluvium, emphasizing how elevated cortisol levels and impaired microcirculation contribute to hair loss, along with potential interventions, including both medicinal and non-medicinal strategies like relaxation techniques and gentle care rituals.
research Stem cell rejuvenation and the role of autophagy in age retardation by caloric restriction: An update
This review examines how caloric restriction could promote autophagy to rejuvenate aging stem cells, though the precise molecular mechanisms remain unclear.
research An Uncontrolled Case Series testing Cryo-Chilled Carbon Dioxide as a Novel Amplification of a Nano-Botanical Multi-Acting Therapy in Advanced Stage Androgenetic alopecia (AGA)
In this case series, researchers reported an unexpectedly rapid and positive response to a topical, hydrogel-based botanical treatment for androgenetic alopecia in both male and female volunteers, achieving significant improvement in hair loss within 90 days instead of the planned 270 days.
research Disrupted cholesterol biosynthesis and hair follicle stem cell impairment in the onset of alopecia
This study found that disrupted cholesterol homeostasis in scalp samples from cicatricial alopecia patients hinders hair regrowth by affecting hair follicle stem cell markers, with resulting effects confirmed in vitro and in animal models.
research Factors Influencing Using Scalp Cryotherapy to Promote Hair Regrowth in Breast Cancer Patients Receiving Chemotherapy
This study found that scalp cryotherapy significantly protected against hair loss during chemotherapy and for two months after, with various factors influencing hair regrowth in breast cancer patients.
research A Phase 1 Study to Investigate the Effects of Cortexolone 17α‐Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity
This phase 1 study reported that after administering supratherapeutic doses of cortexolone 17α‐propionate, a topical antiandrogen intended for hair loss treatment, there was no effect on the QTc interval, indicating no measurable cardiac safety concerns in the concentration range tested.
research The Microanatomy, Cell Replication, and Keratin Gene Expression of Hair Follicles during a Photoperiod-lnduced Growth Cycle in Sheep
The researchers reported that exposure to long days after short-day treatment induced a synchronized, out-of-season wool growth cycle in New Zealand Wiltshire sheep, similar to cycles induced in other species.
research Effectiveness of Xiao-Chai-Hu-Tang for patients of chronic fatigue syndrome:A protocol for systematic review and meta-analysis
The document plans to assess if Xiao-Chai-Hu-Tang is effective for chronic fatigue syndrome but has no results yet.
research CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia
This study found that the CDK4/6 inhibitor palbociclib may protect human hair follicles from the damaging effects of taxane chemotherapy by inducing G1 arrest in stem/progenitor cells.
research Effects Of Hormone Therapy On The Laboratory Profile Of Transgender People: A Scoping Review
This scoping review aims to explore the impact of hormone therapy on the laboratory profiles of transgender people, identify evidence, and highlight literature gaps, particularly in developing countries.
research The local hypothalamic–pituitary–adrenal axis in cultured human dermal papilla cells
This study found that stress hormones, particularly CRF, can inhibit hair growth and induce hair loss by affecting human dermal papilla cells and hair follicles, suggesting a functional HPA axis in these cells.
research ИСПОЛЬЗОВАНИЕ ПОЛИНУКЛЕОТИДОВ В АНТИВОЗРАСТНОЙ ИНЪЕКЦИОННОЙ КОСМЕТОЛОГИИ С ПОЗИЦИИ ДОКАЗАТЕЛЬНОЙ МЕДИЦИНЫ
This study discusses how polynucleotide-based cosmetic products can improve aging skin in patients with particular morphotypes by restoring cellular metabolism, enhancing microcirculation, and promoting intracellular matrix remodeling, offering potential benefits for reversing chrono- and photo-aging and aiding tissue recovery after cosmetic or surgical procedures.
research A novel framework for integrative hair longevity management
This study outlines a framework for hair longevity that emphasizes prevention and integrative management of androgenetic alopecia by proposing a multi-targeted approach combining treatments, nutrition, and lifestyle changes.
research Biology of the Hair Follicle: The Basics
This article discusses the hair follicle's regenerative cycles and the molecular mechanisms influencing them, emphasizing the need for therapeutic targeting of the "hair cycle clock" to manage hair growth disorders, without reporting new research findings.
research Stereocontrolled synthesis of all eight stereoisomers of the putative anti-androgen cyoctol
In this study, all stereoisomers of cyoctol were synthesized and tested, revealing that contrary to initial patent claims, cyoctol does not function as an anti-androgen.
research Management of chronic diffuse hair fall with constitutional homeopathy: A case report
This case report from Dr Batra’s® Homeopathy Clinic describes significant improvement in a middle-aged woman's chronic hair loss and scalp visibility through individualized homeopathic treatment, nutritional adjustments, and regular monitoring over a year, as evidenced by patient-reported outcomes and clinical assessments.
research Topical RT1640 treatment effectively reverses gray hair and stem cell loss in a mouse model of radiation‐induced canities
In this study, RT1640 was found to promote hair pigment system regeneration and expand melanocyte stem cell pools in a mouse model, suggesting potential applications for aging-related hair disorders.