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    Did you mean Chromatin Remodeling?
    Glossary Chromatin Remodeling

    restructuring of DNA-protein complexes to regulate gene expression

    Chromatin remodeling refers to the dynamic modification of the structure of chromatin, which is the complex of DNA and proteins in the nucleus of a cell. This process involves the repositioning or restructuring of nucleosomes (the basic units of chromatin) to either expose or hide specific DNA regions, thereby regulating gene expression. For a layperson, it's like rearranging books on a shelf to make certain ones easier to read, while for a professional, it involves understanding the specific molecular mechanisms and enzymes, such as ATP-dependent chromatin remodelers, that facilitate these changes.

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    1. ATP-dependent chromatin remodeling during mammalian development Development · 2016 · 182 citations
    2. p63 regulates <i>Satb1</i> to control tissue-specific chromatin remodeling during development of the epidermis The Journal of Cell Biology · 2011 · 166 citations
    3. 972 The ATP-dependent chromatin remodeler BRG1 controls epidermal keratinocytes migration during human cutaneous wound healing Journal of Investigative Dermatology · 2019
    4. The Role of ATP-dependent Chromatin Remodeling in the Control of Epidermal Differentiation and Skin Stem Cell Activity Stem cell biology and regenerative medicine · 2018
    5. 707 Chromatin remodeler Lymphoid-specific helicase (Lsh) is a critical determinant controlling postnatal epidermal growth, differentiation and response to injury Journal of Investigative Dermatology · 2016
    6. Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression Cell stem cell · 2018 · 85 citations
    7. Hair Follicle Stem Cell Faith Is Dependent on Chromatin Remodeling Capacity Following Low-Dose Radiation Stem cells · 2017 · 13 citations
    8. Linking Morphogen and Chromatin in the Hair Follicle Developmental Cell · 2013
    9. Tailored chromatin modulation to promote tissue regeneration Seminars in Cell & Developmental Biology · 2019 · 10 citations
    10. Second International Symposium—Epigenetic Regulation of Skin Regeneration and Aging: From Chromatin Biology towards the Understanding of Epigenetic Basis of Skin Diseases 2017 · 2 citations
    11. 252 Follicle dermal papilla cells undergo chromatin remodelling processes in vivo and in vitro Journal of Investigative Dermatology · 2017
    12. Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata Frontiers in Immunology · 2025 · 4 citations
    13. Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair Developmental Cell · 2013 · 52 citations
    14. Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets. PubMed · 2016 · 39 citations
    15. Stem Cells behind the Barrier International journal of molecular sciences · 2013 · 22 citations
    16. Integrative analysis of rare copy number variants and gene expression data in alopecia areata implicates an aetiological role for autophagy Experimental Dermatology · 2019 · 20 citations
    17. Interplay of MicroRNA-21 and SATB1 in Epidermal Keratinocytes during Skin Aging Journal of Investigative Dermatology · 2019 · 16 citations
    18. The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates Nature cell biology · 2023 · 6 citations
    19. p63 in skin homeostasis and disease: molecular mechanisms and therapeutic potentials Cell Death Discovery · 2026
    20. Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease Stem cell biology and regenerative medicine · 2018
    21. All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration Stem cell biology and regenerative medicine · 2018
    22. Epigenetic regulation in adult stem cells and cancers Cell & Bioscience · 2013 · 20 citations
    23. Molecular Regulation of Melanocyte Senescence Pigment Cell Research · 2002 · 85 citations
    24. Hairless is a nuclear receptor corepressor essential for skin function Nuclear Receptor Signaling · 2009 · 30 citations
    25. Analysis of hairless corepressor mutants to characterize molecular cooperation with the vitamin D receptor in promoting the mammalian hair cycle Journal of Cellular Biochemistry · 2010 · 22 citations
    26. Le gène<i>hairless</i>de la souris 2006 · 4 citations
    27. Primary TSC2-/meth Cells Induce Follicular Neogenesis in an Innovative TSC Mouse Model International Journal of Molecular Sciences · 2022 · 3 citations
    28. Expanding the Cutaneous Spectrum of Nicolaides‑Baraitser Syndrome: Eczema and Generalized Hair Loss Cureus · 2025
    29. 0846 Wnt signaling drives hair follicle regeneration in wounds by attenuating mechanotransduction in the epidermis Journal of Investigative Dermatology · 2025
    30. Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration Science Advances · 2025