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    Glossary Chromatin Immunoprecipitation

    method to study protein-DNA interactions using specific antibodies

    Chromatin Immunoprecipitation (ChIP) is a laboratory technique used to investigate the interaction between proteins and DNA within the cell. By using specific antibodies to target and isolate a protein of interest, researchers can identify the DNA sequences that are bound by this protein, providing insights into gene regulation and epigenetic mechanisms.

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    1. In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators Nature Cell Biology · 2014 · 173 citations
    2. The Vitamin D Receptor Is Required for Activation of cWnt and Hedgehog Signaling in Keratinocytes Molecular Endocrinology · 2014 · 56 citations
    3. Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells International Journal of Molecular Sciences · 2022 · 8 citations
    4. The Mammalian Hairless Protein as a DNA Binding Phosphoprotein Journal of cellular biochemistry · 2016 · 6 citations
    5. STAT3 Partly Inhibits Cell Proliferation via Direct Negative Regulation of FST Gene Expression Frontiers in genetics · 2021 · 3 citations
    6. Transcription factor FOXC1 positively regulates SFRP1 expression in androgenetic alopecia Experimental Cell Research · 2021
    7. The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target during Hair Follicle and Nail Differentiation 2010 · 68 citations
    8. Linking Morphogen and Chromatin in the Hair Follicle Developmental Cell · 2013
    9. Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease Stem cell biology and regenerative medicine · 2018
    10. Genome-wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage Cell stem cell · 2011 · 191 citations
    11. p63 regulates <i>Satb1</i> to control tissue-specific chromatin remodeling during development of the epidermis The Journal of Cell Biology · 2011 · 166 citations
    12. Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression Cell stem cell · 2018 · 85 citations
    13. Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair Developmental Cell · 2013 · 52 citations
    14. Epigenetic regulation in adult stem cells and cancers Cell & Bioscience · 2013 · 20 citations
    15. Hairless is a nuclear receptor corepressor essential for skin function Nuclear Receptor Signaling · 2009 · 30 citations
    16. The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates Nature cell biology · 2023 · 6 citations
    17. Stem and cancer cells Wnt long telomeres Nature Cell Biology · 2012
    18. Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice Nature · 2015 · 321 citations
    19. Editorial: Stem cell exhaustion in aging Frontiers in Aging · 2024 · 13 citations
    20. Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer Nature Reviews Genetics · 2018 · 124 citations
    21. GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states PLOS Genetics · 2017 · 38 citations
    22. Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken Development · 2022 · 10 citations
    23. Transcriptional and epigenetic mechanisms governing epidermal stem cell regulation Frontiers in Cell and Developmental Biology · 2026
    24. Epigenetic and transcriptional profiling of secondary hair follicle stem cells during cashmere growth Scientific Data · 2026
    25. Dynamics and Epigenetics of the Epidermal Differentiation Complex Epigenomes · 2024
    26. Mettl3-catalyzed m <sup>6</sup> A regulates histone modifier and modification expression in self-renewing somatic tissue Science Advances · 2023 · 24 citations
    27. Identification of A p300–SP1–BRD4 Transcriptional Axis as a Key Driver of AR Hyperactivation in Polycystic Ovarian Syndrome Advanced Science · 2026
    28. Synchronizing actin and microtubules for axonal branching Nature Cell Biology · 2012 · 3 citations
    29. Watching hair grow Nature Cell Biology · 2012
    30. Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity Developmental Biology · 2008 · 28 citations