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Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Jojoba oil has many uses beyond skincare, including health benefits and pharmaceutical applications.

More research is needed to understand how testosterone is maintained in adult males.

Long-term anabolic steroid use can lead to heart and metabolic health issues.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.

Mild essential fatty acid deficiency can cause health issues and is worsened by low-fat diets.

Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.

Hair texture changes with age due to varying levels of lipids.

Eastern Red Bat hair contains various glycerophospholipids, mainly phosphatidylcholine.

Skin changes can indicate starvation and nutritional deficiencies in anorexia nervosa.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

The normal human prostate does not significantly affect blood DHT levels.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Non-obese women with hair loss have higher heart disease risk.

Ethanol pretreatment affects drug penetration through skin and hair follicles.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Sweet potato shochu oil and its components may effectively promote hair growth.

Possible link between hair loss and metabolic syndrome, with RANTES as a potential clue.

Kolaviron and quercetin may help treat prostate issues.

Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.