15 citations,
August 2021 in “Reviews in endocrine and metabolic disorders” COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.
58 citations,
January 2013 in “The Journal of Clinical Endocrinology and Metabolism” Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.
28 citations,
October 2018 in “Clinical Obstetrics and Gynecology” Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.
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42 citations,
April 2011 in “European Journal of Dermatology” Early balding men may have insulin resistance, but lifestyle changes can help.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
44 citations,
April 2008 in “The Journal of Clinical Endocrinology & Metabolism” Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.
42 citations,
September 2007 in “The Journal of Clinical Endocrinology and Metabolism” The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.
92 citations,
November 2003 in “The Journals of Gerontology” Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.
1 citations,
July 2015 in “Cambridge University Press eBooks” Testosterone therapy can improve sexual function in women but long-term safety is unclear.
34 citations,
February 2013 in “The Journal of Clinical Endocrinology and Metabolism” Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.
August 1996 in “Journal of Pediatric and Adolescent Gynecology” The document concludes that PCOS in adolescents is complex and requires comprehensive care to manage its symptoms and associated health risks.
22 citations,
January 1995 in “The American Journal of Medicine” Newer low-dose oral contraceptives with less androgenic effects improve patient compliance.
April 2017 in “European Psychiatry” An older woman had false beliefs after taking a depression medication, which stopped when she stopped the medication.
9 citations,
March 2020 in “Gene” Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.
125 citations,
January 1999 in “Drugs” Finasteride effectively treats baldness but may cause sexual side effects.
16 citations,
September 2018 in “Clinical Biochemistry” The document concludes that more research is needed to fully understand the causes of PCOS.
November 2018 in “International Journal of Current Pharmaceutical Research” PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.
30 citations,
September 2017 in “Clinics in Dermatology” Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.
2 citations,
February 2023 in “BMC women's health” Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.
1 citations,
June 2023 in “Nutrients” Vitamin D deficiency is linked to a higher chance of metabolic syndrome in women with PCOS.
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378 citations,
November 2011 in “Human reproduction update” Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.
36 citations,
January 2017 in “Journal of Obstetrics and Gynaecology Research” The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.
251 citations,
October 2014 in “The Journal of Clinical Endocrinology & Metabolism” The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
114 citations,
January 2014 in “World Journal of Gastroenterology” People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.
369 citations,
June 2013 in “Biochimie” Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.
271 citations,
June 2013 in “Human Reproduction” PCOS is common among Chinese women of reproductive age and linked to serious metabolic and reproductive issues, especially in obese women.
317 citations,
April 2018 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
Adequate vitamin D might lower, and high hair chromium might increase DNA damage in obese women.
4 citations,
November 2022 in “Acta dermato-venereologica” People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.
17 citations,
May 2012 in “Clinical Endocrinology” Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.