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Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.

Young adults who had liver disease as children often experience significant health problems and frequently need transplants.

Neuropathic pruritus is a commonly overlooked and wrongly diagnosed type of chronic itching that is hard to treat.

A man wrongly believed he had parasites, showing that delusional infestation can affect men and is often linked with other psychiatric issues, but can be treated with antipsychotics.

The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.

Early detection and treatment of primary biliary cirrhosis and related autoimmune diseases improve outcomes.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

KATP channels may help reduce itching in liver disease.

Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.

A certain medication improved severe itching in a boy with liver and bowel disease by reducing histamine levels, suggesting a new treatment target.

The pseudo 'fringe sign' can also appear in frontal fibrosing alopecia, not just in traction alopecia, showing that this condition may be more common than thought.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Most pregnant women experience skin changes like darkening and stretch marks, and some may have skin conditions that usually get better after giving birth.

The conclusion is that CD90 is not a specific marker for fibroblast subtypes and better methods are needed to identify them.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

COVID-19 can cause skin issues like chilblains and rashes, which may help in early detection, especially in patients without other symptoms.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Testosterone treatment in transgender teens can worsen acne, requiring careful treatment due to mental health and medication side effects.