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Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

FOXN1 gene variants cause low T cells and immune issues from birth.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.

Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Taking too many vitamin and mineral supplements can cause serious health problems.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

Eye exams are crucial for kids with 13q deletion syndrome, tamoxifen can cause vision loss, Propecia may lead to cataracts, Lipoid Proteinosis causes skin bumps, and OCT is useful for diagnosing macular diseases.

The document says menstruation is important for women's health, discusses menstrual disorders, and suggests personalized treatment options.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

Obesity is linked to various skin disorders, which can help with early diagnosis and prevention of long-term health issues.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

COVID-19 may harm male fertility and damage the reproductive system.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Most skin changes during pregnancy are harmless and moles don't significantly change, but many women experience pigmentation changes due to hormones and sun exposure.

The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.