research Mitoxantrone
Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.
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research Doxil (Caelyx): An Exploratory Study with Pharmacokinetics in Patients with Hormone-Refractory Prostate Cancer
Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.
research Traditional Anticoagulants and Hair Loss: A Role for Direct Oral Anticoagulants? A Review of the Literature
Some new oral anticoagulants may also cause hair loss and might not be better than traditional ones for preventing hair loss.
research Undariopsis Peterseniana Promotes Hair Growth by the Activation of Wnt/β-Catenin and ERK Pathways
Undariopsis peterseniana extract helps hair grow by activating certain cell growth pathways and could be a new treatment for hair loss.
research Formestane Preferred as Second-Line Therapy in Advanced Breast Cancer
Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.
research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis
Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
research Anthracycline Analogs: The Past, Present, And Future
Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.
research Mitoxantrone
Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.
research Gemcitabine in Combination with Vinorelbine in Elderly Patients with Anthracycline- and Taxane-Pretreated Metastatic Breast Cancer
The combination of gemcitabine and vinorelbine is effective and safe for treating elderly patients with advanced breast cancer previously treated with anthracyclines and taxanes.
research Use of a Healthcare Claims Database for Post-Marketing Safety Assessments of Eribulin in Japan: A Comparative Assessment with a Prospective Post-Marketing Surveillance Study
Healthcare claims databases can help monitor drug safety, but may report adverse events differently than direct surveillance.
research Effectiveness and Safety of a New Hyaluronic Acid Injectable for Augmentation and Correction of Chin Retrusion
HASHA is a safe and effective option for chin augmentation.
research Pharmacokinetics, Toxicity, and Activity of Intravenous Dextran Sulfate in Human Immunodeficiency Virus Infection
Dextran sulfate was found to be toxic and ineffective for treating HIV.
research Reversible Alopecia Universalis During Treatment with PEG-Interferon and Ribavirin for Chronic Hepatitis C
Some patients may experience temporary total hair loss from hepatitis C treatment with PEG-interferon and ribavirin.
research Factors Associated with Anti-SARS-CoV-2 IgG Antibody Production in Patients Convalescing from COVID-19
Men, diabetes, and high inflammation levels lead to higher COVID-19 antibodies.
research In Vitro Analysis of Finasteride Activity Against Candida Albicans Urinary Biofilm Formation and Filamentation
Finasteride effectively prevents biofilm formation and treats preformed biofilms, but requires high doses.
research Advances in Genetic and Molecular Understanding of Omenn Syndrome: Implications for the Future
Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.
research Sex Hormones and Related Compounds, Including Hormonal Contraceptives
Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.
research Olorofim Effectively Eradicates Dermatophytes In Vitro and In Vivo
Olorofim effectively treats fungal skin infections.
research Oral Minoxidil in Trichology: A Review
Oral minoxidil helps with hair growth but needs more research to fully understand its effectiveness and safety.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Minoxidil Is a Potential Neuroprotective Drug for Paclitaxel-Induced Peripheral Neuropathy
Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.
research Aminopterin in the Treatment of Leukemia in Children
Aminopterin was somewhat effective in acute lymphoblastic leukemia in children but did not increase survival time.
research Repurposing Kir6/SUR2 Channel Activator Minoxidil to Arrest Growth of Gynecologic Cancers
Minoxidil can stop the growth of ovarian cancer cells without harming the heart.
research Pharmacological Treatment of Alopecia
Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.
research Retinoids: New Uses and New Synthetic Agents
New retinoids are effective for various skin conditions and are being developed to have fewer side effects.
research The Biology of Hair Follicles
Hair follicle biology advancements may lead to better hair growth disorder treatments.
research Effects of Dermatological Medications on Male Fertility
Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.
research The Therapeutic Use of Topical Minoxidil
Minoxidil effectively treats hair loss, with better results in women.
research Telogen Alopecia Induced by UV Rays
UV rays can cause a type of hair loss known as telogen alopecia.
research Role of Liposomal Anthracyclines in the Treatment of Multiple Myeloma
Liposomal anthracyclines are effective and safer for treating multiple myeloma, especially in elderly patients.