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research Riboflavin-responsive glutaryl CoA dehydrogenase deficiency
This study reports that riboflavin may increase enzymatic activity in a GCDH-deficient patient with specific mutations, but doesn't fully normalize urinary organic acid levels.
research Cronkhite-Canada Syndrome (CCS)—A Rare Case Report
This report presents a case of Cronkhite-Canada syndrome in an elderly Indian male, adding to the approximately 450 cases documented worldwide, but introduces no new results about the condition.
research 1500 Grafts Using the CO2 Silk Touch Laser, Choi Transplanters, and Calvitron Hair Tomer
This article describes a surgical technique combining CO2 SilkTouch Laser and Calvitron Hair Transplant System that offers a natural-looking hairline with moderate session length and minimal bleeding, but reports no new clinical outcomes.
research The G60S Connexin43 Mutant Regulates Hair Growth and Hair Fiber Morphology in a Mouse Model of Human Oculodentodigital Dysplasia
This study observed that mice with a Cx43 mutation exhibited slower and asynchronous hair regrowth with severe cuticle weathering, mimicking aspects of hair phenotype in some ODDD patients.
research The effect of GGC and CAG repeat polymorphisms on the androgen receptor gene in response to finasteride therapy in men with androgenetic alopecia
This study found that a lower number of GGC sequences in the androgen receptor gene was associated with better clinical response to finasteride in male androgenetic alopecia patients.
research Insights from real-world data: clinical features and treatment patterns of Compound Jinqiancao Granules in patients with prostatitis
This study analyzed real-world clinical data to describe the characteristics and medication patterns of Compound Jinqiancao Granules used to treat prostatitis, highlighting prevalent age groups, common co-medications, and traditional Chinese medicine principles, while noting the limitations in drawing causal inferences due to study design.
research Phenotypic, transcriptomic, and genomic analyses reveal the spatiotemporal patterns and associated genes of coarse hair density in goats
This study used high-resolution imaging and genetic analysis to investigate hair density in the Dazu black goat, identifying key genes like GJA1 and GPRC5D involved in follicle development and maintenance, and highlighted their role in animal hair density regulation.
research Classified Ads
This announcement describes job openings at a boutique hair restoration center in Atlanta and reports no clinical results; it emphasizes quality over quantity in their procedures.
research Hutchinson-Gilford syndrome: History, causes, phenotype and research advances
This review discusses Hutchinson-Gilford Progeria Syndrome, its symptomatology, and the progress in developing treatment strategies, emphasizing that while a cure remains elusive, advances in understanding the disease's molecular mechanisms show promise for future approaches.
research Status of sex reassignment surgery for gender identity disorder in Japan
This review discusses gender identity disorder in Japan, highlighting the high prevalence and challenges in accessing appropriate treatment, and calls for wider understanding among medical professionals.
research Lamellar ichthyosis with pseudoexon activation in the transglutaminase 1 gene
This case report describes a 12-year-old boy with severe skin scaling due to novel compound heterozygous null truncation mutations in the TGM1 gene, resulting in loss of transglutaminase 1 activity.
research Re: Clomiphene Citrate and Human Chorionic Gonadotropin are Both Effective in Restoring Testosterone in Hypogonadism: A Short-Course Randomized Study
This study found that both Clomiphene Citrate and Human Chorionic Gonadotropin were effective in restoring testosterone levels in men with hypogonadism, as demonstrated in a short-course randomized study.
research ICG laser therapy of acne vulgaris
This study found that multiple treatments combining NIR laser phototherapy with ICG significantly reduced inflammation and improved skin condition in acne without side effects.
research Cases Report the Cronkhite-Canada Syndrome
This review discusses Cronkhite-Canada syndrome, highlighting a relatively mild case and suggesting that it may be a more benign and possibly reversible condition with treatment, but reports no new clinical results.
research Endocrine Therapy of Adult Gender-Incongruent Individuals Seeking Gender Reaffirmation
This document provides protocols for gender-affirming hormone therapy in India, highlighting the need for research on outcomes and adverse events in adults receiving such therapy; it reports no new results.
research Diffuse Gastrointestinal Polyposis With Skin, Hair, and Nail Changes
This report describes a case of Cronkhite-Canada syndrome diagnosed in a 54-year-old man with symptoms including gastrointestinal polyps, alopecia, skin hyperpigmentation, and severe diarrhea, who experienced significant symptom improvement with azathioprine.
research Episodic Bilateral Corneal Edema Caused by Hair Groom Gel
research 396 A novel investigator global assessment score for the evaluation of keratosis pilaris
In this study, the KPAI and KP-IGA scoring systems for assessing keratosis pilaris showed excellent interrater and intrarater reliability, offering standardized measures for clinical and research use.
research Computer physics communications instructions to authors (third revision)
research Cronkhite-Canada Syndrome Associated With Superficial Esophageal Carcinoma: A Case Report and Literature Review
This case report highlights a rare instance of esophageal carcinoma in a patient with Cronkhite-Canada syndrome, emphasizing the importance of endoscopic surveillance for malignant gastrointestinal tumors in these patients.
research Safety, tolerability, and pharmacokinetics of CG2001 in Chinese adult male subjects with androgenetic alopecia: a randomized, double-blind, placebo-controlled, single- and multi-doses, phase 1 clinical study
This research describes CG2001's promising safety profile and reduced systemic exposure as an alternative to finasteride, supporting its further development for androgenic alopecia treatment in future trials.
research Identification and characterization of an antisense RNA transcript (gfg) from the human basic fibroblast growth factor gene.
Researchers found an RNA transcript that might help control a growth factor linked to tumor development.
research Geschlechtsinkongruenz – Definition, Diagnosestellung und Transitionsoptionen
This article reviews the diagnostics and medical transition options for adults with gender incongruence, reports no new clinical results, and highlights the importance of primary care knowledge in managing these patients.
research 1351 Investigation of the molecular identity of the junctional zone in human
This study suggests that GATA6 is a key regulator of the upper pilo-sebaceous unit homeostasis and differentiation in human skin.
research Position effect on FGF13 associated with X-linked congenital generalized hypertrichosis
This study found a significant association between reduced FGF13 levels and X-linked congenital generalized hypertrichosis, suggesting FGF13's potential role in hair follicle growth and the hair cycle.
research Safety, tolerability, and pharmacokinetics of CG2001 in Chinese adult male subjects with androgenetic alopecia: a randomized, double-blind, placebo-controlled, single- and multi-doses, phase 1 clinical study
This study found that the novel alcohol-free topical foam CG2001, combining minoxidil and finasteride, was safe and well-tolerated in Chinese males with androgenetic alopecia, with significantly lower systemic exposure to finasteride compared to oral administration, potentially reducing sexual side effects.
research Chinese Herbal Medicine, Guilu Erxian Glue, as Alternative Medicine for Adverse Side Effects of Chemotherapy in Doxorubicin-Treated Cell and Mouse Models
This study found that Guilu Erxian Glue significantly alleviates various doxorubicin-induced side effects in mice, enhancing exercise capacity and reducing oxidative stress and inflammation.
research EGCG-Biotin-Pal-GHK composition modulates TGF-β and BMP pathways in scalp microenvironment for treating stress-induced alopecia
research Cronkhite–Canada Syndrome With Multiple Mesenteric Lymphadenopathy: A Case Report
In this case study, a 78-year-old Japanese woman with Cronkhite-Canada syndrome experienced mesenteric lymphadenopathy, which reduced in size after treatment with the corticosteroid prednisolone. This suggests that mesenteric lymphadenopathy, though uncommon in CCS, may respond to steroid therapy.