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An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Doctors need to be better prepared to assess and treat obesity in patients.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Scalp cooling can reduce chemotherapy-induced hair loss and should be available in all hospitals.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Both mouse and rat models are effective for testing alopecia areata treatments.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

SHBG may be a useful early indicator and treatment target for PCOS.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Drug addicts often have scars, skin color changes, blocked veins, and bruising, with severe ulcers from barbiturate injections.

Burn reconstruction improves with new techniques, materials, and tissue engineering.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.