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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Nerves and chemicals in the body can affect hair growth and loss.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Skin has specialized touch receptors that can tell different sensations apart.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.