6 citations
,
May 2018 in “Plant Cell, Tissue and Organ Culture (PCTOC)” This study found that adjusting plant growth conditions, such as the use of elicitors like yeast extract and methyl jasmonate, increased wedelolactone production in Eclipta alba cell suspension culture.
177 citations
,
November 2002 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, stable types of leucoderma such as segmental vitiligo and piebaldism showed 100% repigmentation after melanocyte transplantation, suggesting surgery as the preferred method for these conditions.
67 citations
,
June 2018 in “Engineering in Life Sciences” This review discusses advancements in plant cell culture technology for producing potent natural cosmetic ingredients and reports no new experimental results.
13 citations
,
September 2021 in “Frontiers in Cell and Developmental Biology” This study found that suspension culture was more effective than hydrogel-based systems for maintaining spheroid morphology and differentiation of human iPSC-derived definitive endoderm cells.
This study describes a preliminary examination showing that an intraepidermal injection of autologous epidermal cell suspension contains a significant number of viable cells after 7 days of culture, suggesting potential use in treating skin disorders like alopecia and as an anti-aging therapy.
This study discusses the safety, complications, and limitations of melanocyte transplantation for treating vitiligo, noting that these techniques are generally safe and often combined with medical treatments for repigmenting stable vitiligo macules.
January 2019 in “Springer eBooks” The abstract reports that non-cultured cellular grafting has become a prevalent and cost-effective method for treating stable vitiligo, with safety and effectiveness confirmed by two decades of studies. It critiques strict legislative oversight, suggesting it might unnecessarily increase costs and limit patient access.
17 citations
,
September 2016 in “Stem cells translational medicine” In this study, using stirred-suspension bioreactors to expand dermal stem cells resulted in larger numbers, but had reduced efficiency in forming hair follicle structures compared to static culture conditions.
6 citations
,
October 1989 in “PubMed” This study describes optimized methods for culturing hair cells from 4-day-old C3H mice, leading to successful maintenance of hair-specific cytoskeletal protein expression under the experimental conditions.
3 citations
,
January 2018 in “Methods in molecular biology” This paper describes a protocol for isolating and culturing skin-derived precursors to potentially induce hair growth and regenerate hair follicles, but reports no new experimental findings.
2 citations
,
November 1992 in “Journal of dermatology” This study found that cells isolated from human scalp hair follicles proliferated well in a specific culture medium and possessed keratins characteristic of hair-forming cells.
55 citations
,
April 2017 in “Experimental Dermatology” This article details laboratory methods for isolating and culturing human dermal papilla cells but provides no new experimental results.
5 citations
,
March 2023 in “PubMed” This review discusses the potential of advanced therapy medicinal products for treating vitiligo, highlighting promising results but noting affordability remains a challenge; no new clinical results were reported.
6 citations
,
June 1989 in “Cell Biology International Reports” This study reported that minoxidil affects the physiology of cultured endothelial cells, including reversible suspension of cell proliferation and dose-dependent influence on cell morphology, without significantly altering protein synthesis or inhibiting cell migration.
May 2026 in “Journal of Health and Allied Sciences NU” This study concluded that human epidermal stem cells cultured in MEM-α and EpiLife media with growth factors show high proliferation potential and plasticity, suggesting potential use in skin regenerative medicine.
June 2026 in “Clinical Cosmetic and Investigational Dermatology” In this study, researchers detailed various surgical techniques for treating vitiligo, including tissue grafting and cell transplantation. They highlighted recent advancements and emphasized the need for future studies to explore therapeutic mechanisms and identify biomarkers to enhance surgical efficacy.
This study found that hyaluronic acid increased the size of hair follicle germ-like aggregates and the number of proliferative cells but did not maintain specific markers during the process.
September 2017 in “Journal of Investigative Dermatology” This study found that hyaluronic acid increased the size and cell proliferation of mixed aggregates in a 3D culture model, indicating its role in human hair follicle germ-like structure formation without enhancing dermal papilla cell markers.
17 citations
,
January 1997 in “Cell and Tissue Research” This study found that a serum-free DMEM-F12 medium with 45% oxygen best supports in vitro development and differentiation of human fetal skin, closely mimicking the in vivo state.
8 citations
,
July 2019 in “Cell Proliferation” In this study, researchers developed a chemical cocktail and suspension culture method to transform human dermal fibroblasts into dermal papilla-like cells capable of inducing hair follicle formation in vitro and in vivo.
5 citations
,
March 2017 in “Cell and Tissue Banking” In this study, noncultured autologous skin cells prepared using a tissue homogenizer significantly improved burn wound healing in rats compared to a control treatment.
21 citations
,
October 2009 in “Biochemical Engineering Journal” This review discusses various approaches to treating alopecia, including drug therapy and hair transplantation, but reports no new research findings; the authors highlight the need for novel techniques like cell culturing.
61 citations
,
December 2016 in “The EMBO Journal” This study established a new in vitro culture system that supports the growth and dynamic self-organization of hair follicle stem cells and their progeny, promoting a stable population equilibrium.
4 citations
,
September 2024 in “Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics” This review discusses the potential of 3D cell cultures, particularly Patient-Derived Organoids, in advancing research on liposarcoma by addressing limitations of 2D cultures and animal models but reports no new experimental findings.
88 citations
,
January 2019 in “Journal of Tissue Engineering and Regenerative Medicine” This review discusses current uses and advancements in mesenchymal stem cell-derived conditioned media as a potential regenerative therapy but does not present new clinical findings.
16 citations
,
October 2018 in “Experimental Dermatology” This study suggests that mesenchymal stem cell therapy may improve cell viability and regulate key signaling pathways in vitro for treating alopecia areata.
23 citations
,
November 2015 in “Phytotherapy Research” This study found that cucurbitacin I from bitter melon most effectively inhibited the growth of lung cancer cells and promoted hair cell growth in cell cultures.
38 citations
,
January 2006 in “Journal of Cellular Biochemistry” This study reported the successful isolation of epithelial stem cells from mouse embryonic skin using a simple culture method, with the cells showing the potential to differentiate into multiple cell types.
16 citations
,
August 2019 in “Cell Proliferation” This study found that 3D cultured hair follicle-like constructs, which include keratinocytes and dermal papilla cells, showed improved gene expression and cell interactions relevant to hair follicle development.
11 citations
,
May 2018 in “Philosophical Transactions of the Royal Society B” This review covers recent developments in materials for in vitro and in vivo stem cell manipulation, highlighting innovative substrate properties but does not report new experimental results.