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Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Telocytes might help with skin repair and regeneration.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Use minoxidil for hair loss treatment; assess results after 6 months.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.