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      Cutaneous Complications of Chemotherapeutic Agents

      research Cutaneous complications of chemotherapeutic agents

      172 citations , November 1983 in “Journal of The American Academy of Dermatology”
      This article discusses the cutaneous side effects of various chemotherapeutic agents but reports no new clinical results; the authors emphasize the importance of dermatologists recognizing drug-induced skin reactions to better patient care.
      Fetal Alcohol Syndrome: Current Status of Pathogenesis

      research Fetal Alcohol Syndrome: Current Status of Pathogenesis

      171 citations , October 1990 in “Alcoholism/Alcoholism, clinical and experimental research”
      The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
      Endocrinology of Transgender Medicine

      research Endocrinology of Transgender Medicine

      166 citations , October 2018 in “Endocrine Reviews”
      This review discusses the effects of hormonal treatments on the physical and mental health of transgender individuals, reporting significant reductions in mental health issues following treatment, but calls for more research on long-term and nonbinary outcomes.
      Noninvasive Method for Assessing the Human Circadian Clock Using Hair Follicle Cells

      research Noninvasive method for assessing the human circadian clock using hair follicle cells

      166 citations , August 2010 in “Proceedings of the National Academy of Sciences of the United States of America”
      This study reports a less invasive method for detecting human clock gene expression using hair follicle cells, which accurately reflects individual behavioral rhythms and suggests a time lag issue for rotating shift workers.
      Testosterone Therapy for Transgender Men: Effects and Safety

      research Testosterone therapy for transgender men

      162 citations , April 2016 in “The Lancet Diabetes & Endocrinology”
      This review discusses the effects of testosterone therapy for transgender men, noting desired outcomes and potential risks, but reports no new research findings; the authors highlight a lack of high-quality data due to various study limitations.
      Prostaglandin-Induced Hair Growth

      research Prostaglandin-Induced Hair Growth

      162 citations , August 2002 in “Survey of Ophthalmology”
      This study found that latanoprost induces significant growth and pigmentation of lashes and ancillary hairs, with effects mirroring both brief and chronic treatments observed in patients and animal models.
      Vitamin D and the Skin: Physiology and Pathophysiology

      research Vitamin D and the skin: Physiology and pathophysiology

      158 citations , August 2011 in “Reviews in endocrine and metabolic disorders”
      This review examines the functions of vitamin D and its receptor in skin and explores how these are regulated, reporting no new clinical results.
      Epithelial Stem Cells And Implications For Wound Repair

      research Epithelial stem cells and implications for wound repair

      156 citations , October 2012 in “Seminars in Cell & Developmental Biology”
      This study found that hair follicle stem cells initially contribute to wound re-epithelialization, but long-lasting epidermal cells are primarily derived from a stem cell population in the isthmus portion of hair follicles.
      Minoxidil Use in Dermatology, Side Effects, and Recent Patents

      research Minoxidil Use in Dermatology, Side Effects and Recent Patents

      152 citations , April 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery”
      This review describes minoxidil's hair regrowth mechanism and discusses dermatological applications, but reports no new clinical results, emphasizing the need for regular use and addressing allergic reactions.
      Gender Differences in Skin: A Review of the Literature

      research Gender differences in skin: A review of the literature

      152 citations , December 2007 in “Gender Medicine”
      This review discusses recent advances in understanding gender differences in skin and their implications for dermatologic diseases, but it reports no new experimental results; ongoing research is necessary for translating these insights into clinical practice.
      Alopecia Areata: Overview and Treatment Options

      research Alopecia areata

      151 citations , February 2007 in “International Journal of Dermatology”
      This review explores the causes and mechanisms of alopecia areata and discusses current treatments, reporting no new clinical findings.
      The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

      research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

      144 citations , November 2020 in “Frontiers in immunology”
      This study summarizes how the IL-23/IL-17 axis contributes to inflammatory skin diseases like psoriasis and highlights that biologics targeting this pathway, including monoclonal antibodies against IL-23 and IL-17, have shown efficacy in clinical trials for these conditions.
      Lupus Erythematosus: Systemic and Cutaneous Manifestations

      research Lupus erythematosus: systemic and cutaneous manifestations

      144 citations , September 2006 in “Clinics in Dermatology”
      This article outlines manifestations of systemic lupus erythematosus, noting rapid joint symptom improvement with corticosteroids and antimalarial drug responsiveness for skin symptoms, and links anti-Ro with photosensitive rash and subacute lupus.
      Transplantation Immunology: Solid Organ and Bone Marrow

      research Transplantation immunology: Solid organ and bone marrow

      139 citations , February 2010 in “ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology”
      This review outlines the advancements in organ and tissue transplantation since the discovery of the human MHC and reports no new clinical results.
      Protoporphyrin IX: The Good, the Bad, and the Ugly

      research Protoporphyrin IX: the Good, the Bad, and the Ugly

      138 citations , November 2015 in “Journal of Pharmacology and Experimental Therapeutics”
      This review discusses the mechanisms associated with protoporphyrin IX in living cells and reports no clinical results; the authors emphasize its potential in cancer diagnosis and the risks of toxicity.
      Exosomes for Repair, Regeneration, and Rejuvenation

      research Exosomes for repair, regeneration and rejuvenation

      135 citations , December 2015 in “Expert Opinion on Biological Therapy”
      This review synthesizes recent research on exosomes, highlighting their role as key modulators in regenerative outcomes and suggesting they may offer advantages over stem cell-based therapies in process and regulation.
      Stem Cell Dynamics in the Hair Follicle Niche

      research Stem cell dynamics in the hair follicle niche

      135 citations , December 2013 in “Seminars in Cell & Developmental Biology”
      This review examines the literature on the molecular and cellular makeup of the hair follicle niche and how it influences stem cell behavior during hair regeneration, but does not provide new experimental results.
      Acne, the Skin Microbiome, and Antibiotic Treatment

      research Acne, the Skin Microbiome, and Antibiotic Treatment

      134 citations , January 2019 in “American journal of clinical dermatology”
      This review summarizes recent research on the skin microbiome's role in acne development and how antibiotic treatments affect skin microbes, but it reports no new clinical results.
      The Circadian Clock in Skin

      research The Circadian Clock in Skin

      127 citations , January 2015 in “Journal of Biological Rhythms”
      This review discusses the role of the circadian clock in skin functions such as cell proliferation and UV protection and reports no new results; the authors note its potential in studying immune regulation and seasonal behaviors.
      Regulatory T Cells: The Many Faces of Foxp3

      research Regulatory T Cells: the Many Faces of Foxp3

      125 citations , September 2019 in “Journal of Clinical Immunology”
      This review summarizes recent advances in Treg cell biology, focusing on Foxp3's role in immune regulation and therapeutic reprogramming for immune dysregulatory disorders, but reports no new clinical results.
      Targeting the Janus Kinase Family in Autoimmune Skin Diseases

      research Targeting the Janus Kinase Family in Autoimmune Skin Diseases

      124 citations , October 2019 in “Frontiers in Immunology”
      This review discusses the role of the JAK-STAT pathway in autoimmune skin diseases and suggests potential therapeutic benefits of JAK inhibitors, but reports no new experimental results.