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Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.

The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Created material boosts hair growth and kills bacteria for wound healing.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Red ginseng oil and its components help promote hair regrowth and could treat hair loss.

DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

Mesenchymal stem cells, especially injected into the skin, heal wounds faster and better than chitosan gel or other treatments.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

L-cystine and vitamin B6 at high doses prevented hair loss in mice treated with a chemotherapy drug.

Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.

The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.

Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Microsponges delivery system is a safe, versatile method for controlled drug release in various treatments.

CD2 might be a new treatment target for patchy alopecia areata.