research Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and SCD1 and SOAT1 Activity
Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
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research Toxicity of Repeated Oral Intake of Organic Selenium, Inorganic Selenium, and Selenium Nanoparticles: A Review
Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.
research Prolonged Use of Finasteride-Induced Gonadal Sex Steroids Alterations, DNA Damage, and Menstrual Bleeding in Women
Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.
research Dietary Aspects for Selenium and Selenium Compounds
Getting the right amount of selenium is important for health; too little can cause disease, and too much can lead to toxicity.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Single Nucleotide Polymorphisms Associated with Elevated Alanine Aminotransferase in Patients Receiving Asunaprevir Plus Daclatasvir Combination Therapy for Chronic Hepatitis C
Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.
research What Should It Take to Describe a Substance or Product as 'Sperm-Safe'?
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research New Challenge to Cancer and Longevity
A group has developed therapies that show promise for treating cancer and various other conditions.
research Hair Growth After Gefitinib Treatment
A man's bald spot grew hair after starting cancer treatment with gefitinib.
research Intracrine Androgen Biosynthesis, Metabolism, and Action Revisited
The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
research Selective Androgen Receptor Modulators Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial-Mesenchymal Stem Cell Signaling
SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.
research Selenium And Its Inorganic Compounds: BAT Value Documentation, 2011
Selenium is essential for health, but too much or too little can cause problems; blood selenium levels are a good measure of intake.
research Prostatic Cystic Hyperplasia in a Young Dog: Case Report
A young dog with an enlarged prostate and cysts improved significantly after treatment and surgery.
research Hirsutism II: Treatment
The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.
research Tracing the Cellular Origin of Cancer
Understanding where cancer cells come from helps create better prevention and treatment methods.
research Therapeutic Control of Androgen Action
Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
research Alopecia: The Case for Medical Necessity
Alopecia should be treated as a medical condition because it may increase the risk of serious diseases and psychological issues.
research Hormone Blocking Anticancer Drugs
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
research Metformin and Malignant Tumors: Not Over the Hill
Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Forum
The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.
research Incidence of Liver Toxicity Associated with the Use of Flutamide in Prostate Cancer Patients
Flutamide rarely causes liver toxicity in prostate cancer patients.
research Rat Steroid 5α-Reductase Kinetic Characteristics: Extreme pH-Dependency of the Type II Isozyme in Prostate and Epididymis Homogenates
The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
research Smoothened Receptor Inhibitor Vismodegib for the Treatment of Basal Cell Carcinoma: A Retrospective Analysis of Efficacy and Side Effects
Vismodegib is effective for basal cell carcinoma but has severe side effects.
research Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex
Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.
research Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia
Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.
research Role of 5 Alpha-Reductase Inhibitors in the Management of Prostate Cancer
5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.
research Epidemiology of Skin Cancer in the Mature Patient
Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.
research Characterization of CD4+ Stem Cells of the Skin and Their Role in Skin Homeostasis and Tumorigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Multiple Readout Assay for Hormonal (Androgenic and Antiandrogenic) and Cytotoxic Activity of Plant and Fungal Extracts Based on Differential Prostate Cancer Cell Line Behavior
The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.