2 citations
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September 2011 in “Revista de Ciências Farmacêuticas Básica e Aplicada” This study examined a shampoo containing chili pepper extract and biopolymer microspheres for hair loss treatment, finding that it was well tolerated by volunteers, particularly due to the exfoliation sensation.
May 2025 in “Indian Journal of Pharmacology” In this study, researchers reported that standardized rosemary and capsicum extracts significantly improved hair growth parameters such as follicle density, length, and diameter in rats with testosterone-induced alopecia, suggesting these extracts may aid in more effective natural treatments for androgenetic alopecia.
August 2024 in “Majalah Obat Tradisional” This study found that microemulsions containing ethanol extract of cayenne pepper were effective in enhancing hair growth in rabbits, with the 0.2% concentration achieving the most significant results over a 30-day period, compared to a negative control.
July 2023 in “Research journal of pharmacy and technology” In this study on male rabbits, a hair tonic formulated with delipidated ethanol extract of Capsicum frutescens L. leaves at concentrations of 5%, 10%, and 20% promoted hair growth more effectively than a placebo and similar to 2% Minoxidil at the highest concentration.
June 2021 in “Journal of Pharmaceutical Care Anwar Medika” This study investigated the physical stability of hair tonic formulations made from ethanol extract of cayenne pepper leaves, finding that formulations with specific concentrations of propylene glycol and ethanol had good physical stability.
December 2020 in “Jurnal Kedokteran Hewan” In this study, researchers found that cayenne leaf extract significantly enhanced hair length and quantity in mice, with a 10% concentration being the most effective for stimulating growth.
24 citations
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January 2020 in “International Journal of Molecular Sciences” This review discusses the potential benefits of flavonoid-containing botanicals, such as Panax ginseng, in reducing hair loss and promoting hair growth, but reports no new experimental results.
May 2013 in “International journal of innovative research and development” This article discusses a hypothetical model of androgenic hair trichophore composed of various chemical components, but it reports no new empirical findings; the authors emphasize the model's potential impact on hair cosmetics.
January 2024 in “Estetologia Medyczna i Kosmetologia” In this study analyzing trichological shampoos on the Polish market, researchers reported that most active ingredients claimed to combat hair loss were found in only one product each, questioning the scientific evidence supporting these claims.
14 citations
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March 2019 in “Plant methods” This study introduced a new adaptive microrhizotron for non-destructive observation of pepper root traits, finding that specific installation patterns significantly enhanced root interception probability while effectively measuring root architecture for plant research.
28 citations
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March 1942 in “Journal of Endocrinology” This article reviews studies on thyroid influence on hair growth, noting varied results, including accelerated growth in some normal and underfed rats after thyroid administration, but reports no clinical results.
16 citations
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January 1980 in “Planta Medica” This study found that alcoholic extracts of Cinchona succirubra, Dictamnus dasycarpus, Brassica juncea, and Sophora flavescens promoted hair growth in 5-week-old mice.
14 citations
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November 2013 in “Journal of the American Society for Horticultural Science” This study observed that glycine inhibited root growth and stimulated root hair development in habanero pepper seedlings, with ethylene signaling suggested to mediate these effects.
7 citations
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July 2018 in “Journal of Functional Biomaterials” This study evaluated a new anti-baldness product, IPSTiC patch hair, designed to treat androgenetic alopecia, and reported that it effectively inhibits NO radical and 5α-reductase activity while maintaining safety and stability, suggesting its potential for topical use.
January 2019 in “The Pharma Innovation Journal” This study found that optimal antioxidant properties of a cream-mask, as indicated by extended Paramecium caudatum motor activity in a toxic environment, were achieved with 10% Sophora japonica tincture and 5% Serenoa repens dry extract.
581 citations
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February 1998 in “The American Journal of Medicine” This review discusses the potential adverse effects of herbal remedies, such as allergic reactions and drug interactions, and reports no new clinical findings; the authors suggest the risks might be underestimated.
81 citations
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June 2010 in “Journal of Dermatological Treatment” This review discusses recent advancements in hair rejuvenation strategies and assesses the potential of herbal drugs as safer alternatives, but reports no new clinical results.
67 citations
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June 2018 in “Engineering in Life Sciences” This review discusses advancements in plant cell culture technology for producing potent natural cosmetic ingredients and reports no new experimental results.
48 citations
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November 1992 in “International Journal of Dermatology” This article discusses the history and terminology of toxic epidermal necrolysis but reports no new clinical results.
41 citations
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July 2015 in “Current Drug Discovery Technologies” This review discusses various plants and herbal formulations traditionally used for hair growth and notes their potential as safer alternatives to synthetic hair loss treatments, but reports no new clinical results.
39 citations
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September 2016 in “Expert Opinion on Drug Delivery” This review explores how colloidal drug delivery systems can enhance the stability, absorption, and bioavailability of phytochemicals, potentially rediscovering ancient compounds' therapeutic benefits and overcoming limitations like poor solubility and bioavailability.
39 citations
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September 2013 in “Journal of Cosmetic Dermatology” This review summarizes causes and treatments of androgenetic alopecia with a focus on herbs as potential alternatives, but reports no new results and suggests more research is needed to validate these options.
36 citations
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September 2019 in “Journal of Herbal Medicine” This review explores research on nanoformulations for enhancing the topical delivery of herbal medicines, noting potential benefits like improved bioavailability and sustained delivery, and emphasizes the need for safety and toxicity guidelines in developing these novel drug delivery systems.
22 citations
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July 2017 in “BMC complementary and alternative medicine” This study documented the use of 41 plant species in the West Bank for treating hair and scalp disorders, highlighting their folkloric significance and potential for new cosmetic and cosmeceutical products.
22 citations
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March 2000 in “Clinics in Dermatology” This study developed a method using HPLC with UV-DAD and ESI-MS detection to identify prohibited substances like minoxidil and hormones in cosmetic products advertised online for hair loss and skin conditions.
16 citations
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September 2018 in “Journal of Ethnopharmacology” This review discusses the role of inheritance, androgens, and microinflammation in androgenetic alopecia and suggests some plant-based folk remedies may help address these factors but reports no new clinical results.
13 citations
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January 2016 in “Journal of cosmetology & trichology” This review discusses the emerging pathophysiological factors and potential new therapies for androgenetic alopecia beyond traditional treatments, but reports no new results.
12 citations
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July 2025 in “Journal of Clinical and Translational Hepatology” This review discusses how targeting TGF-β with specific inhibitors, including components from Traditional Chinese Medicine, may help reduce liver fibrosis by acting through various signaling pathways.
12 citations
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November 1945 in “Archives of dermatology” In this study, hair color changes in piebald rats after skin grafting suggest that such changes are more likely due to the surgical process than the new environment.
10 citations
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June 2019 in “International Journal of Cosmetic Science” This review discusses the potential benefits of phytochemicals for hair care and emphasizes the need for more robust preclinical and clinical studies, without reporting new clinical results.