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Omics techniques are needed to understand the scalp microbiome's role in alopecia areata for new treatments.

The calcineurin/NFAT pathway plays a significant role in the development and growth of a type of skin cancer called cutaneous squamous cell carcinoma.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.

Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.

Women with PCOS have higher risks of heart disease, type 2 diabetes, and endometrial cancer.

Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.

Excessive hair growth in women, often from high androgen levels, is usually caused by PCOS, and can be treated with hair removal, medication, and possibly weight loss.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Sulforaphane from broccoli can help protect skin from sun damage.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Acne is the most common skin problem in Brazil, with a need for improved dermatological care and health education, especially for the public sector and black-skinned individuals.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

Telogen effluvium is a hair loss condition with acute cases resolving quickly and chronic cases potentially lasting longer, sometimes requiring treatment.