Search
for
Sort by
Research
210-240 / 1000+ results
research CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells
CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.
research CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells
CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.
research Differential Expression of CXCL12 in Human and Mouse Hair: Androgens Induce CXCL12 in Human Dermal Papilla and Dermal Sheath Cup
This study observed that CXCL12 is highly co-expressed with androgen receptors in human hair follicle cells, and its inhibition via antibodies increased hair length, suggesting a potential treatment strategy for androgenic alopecia.
research Regulatory role of LEF-1 in the proliferation of Arbas White Cashmere goat dermal papilla cells
This study found that LEF-1 expression influences dermal papilla cells' proliferation through Wnt signaling, impacting the potential for cashmere yield improvement.
research Hair Loss Following Kerion Celsi‐A Follow‐up Examination
This study found that hair regrowth after griseofulvin treatment for kerion Celsi was significantly reduced in previously affected areas compared to unaffected areas in 18 patients.
research Nε-(carboxymethyl) lysine represses hair follicle formation by inhibiting Sonic hedgehog expression in a NF-κB-independent manner
In this study, injecting Nε-(carboxymethyl) lysine into skin tissue weakened hair shaft and follicle formation, likely by inhibiting cell proliferation and migration needed for hair follicle morphogenesis.
research Transcription Factor DLX5 Promotes Hair Follicle Stem Cell Differentiation by Regulating the c-MYC/microRNA-29c-3p/NSD1 Axis
This study demonstrates that the transcription factor DLX5 can promote hair follicle stem cell differentiation through regulating the c-MYC/miR-29c-3p/NSD1 axis.
research Long-term expansion of basal cells and the novel differentiation methods identify mechanisms for switching Claudin expression in normal epithelia
This study developed a culture method to expand and differentiate primary mammary basal cells, identifying key transcription factors like EGR1 and ELF3 that influence Claudin expression and actin organization, offering insights into epithelial cell biology and potential applications in related research fields.
research EDA Missense Variant in a Cat with X-Linked Hypohidrotic Ectodermal Dysplasia
This study identified a missense variant in the EDA gene of a male cat, which likely caused hypohidrotic ectodermal dysplasia, characterized by hair and teeth abnormalities; this represents the first report of such a genetic condition in cats.
research Synergistic Trichogenic Efficacy of Wedelia chinensis and Cassytha filiformis Emulgel in Murine Models
This study evaluated an herbal emulgel formulation containing extracts from Wedelia chinensis and Cassytha filiformis for hair growth promotion in rats, finding that the combined formulation significantly increased hair growth compared to both individual extracts and the control group.
research Immunohistochemical Expression of the ${\alpha}$ - and ${\gamma}$ -catenin in the Fetal Skin Development
This study found that in fetal skin development, both α- and β-catenins showed similar expression patterns, indicating their related roles in the development of the epidermis and skin appendages.
research Alkaline Phosphatase–Regulated C–C Motif Chemokine Ligand 5 (CCL5) Functions as a Critical Mediator of Hair Follicle Neogenesis
research Expression of hair-related keratins in a soft epithelium: Subpopulations of human and mouse dorsal tongue keratinocytes express keratin markers for hair-, skin- and esophageal-types of differentiation
Hoxc13 is important for hair and tongue development by controlling hair keratin genes.
research Faculty Opinions recommendation of Stem cell niche exit in C. elegans via orientation and segregation of daughter cells by a cryptic cell outside the niche.
This study discovered a novel mechanism by which germ stem cells exit their niche in C. elegans, involving thin membranous protrusions from adjacent somatic gonad cells.
research Cell Cycle Regulation and Regeneration
This study found similarities in the regeneration processes of MRL mouse ears and axolotl limbs, involving G2 cell cycle arrest and nerve-dependent mitosis, but the role of p21 in axolotl limb regeneration remains uncertain.
research Connexin mutations in human disease
This review discusses the role of connexin mutations in various human disorders, highlighting their impact on ectodermal epithelial phenotypes like hearing loss and skin abnormalities, but it presents no new clinical findings.
research Cepharanthine attenuates pulmonary fibrosis via modulating macrophage M2 polarization
This study demonstrated that CEP may effectively treat pulmonary fibrosis by inhibiting fibroblast activation through regulating macrophage M2 polarization and decreasing fibrosis-associated factors, suggesting a new avenue for future research in this area.
research Deletion of the Sox21 gene drastically affects hair lipids
This study found that, despite the unchanged total level of 18-MEA, deletion of the Sox21 gene disrupts its attachment to the hair cuticle, increases cholesterol sulphate levels, and differentially affects ceramide composition.
research μ-Crystallin, Thyroid Hormone-binding Protein, is Expressed Abundantly in the Murine Inner Root Sheath Cells
This study found that mu-crystallin gene expression in mouse skin is highest during the anagen phase of hair development, suggesting its possible role in hair follicle growth.
research Ultrastructure of two types of glandular hairs of salvia farinacea benth during development
Capitate trichomes have more endoplasmic reticulum and vacuoles, while peltate trichomes have more plastids and larger subcuticular spaces.
research Expression of MAEG, a novel basement membrane protein, in mouse hair follicle morphogenesis
This study suggests that the MAEG protein may facilitate epithelial–mesenchymal interactions during hair follicle development by binding to RGD-binding integrins like α8β1.
research Epilating Effect of Cystaselenonine on Induced Hair Growth in Mice
In this study, cystaselenonine treatment in mice resulted in hair loss limited to older growing hairs and delayed regrowth, while also causing temporary weight loss.
research Novel circRNAs from cashmere goats: Discovery, integrated regulatory network, and their putative roles in the regeneration and growth of secondary hair follicles
This study identified 21 novel circular RNAs in cashmere goats, with nine significantly more expressed during the anagen phase of hair follicle growth, suggesting roles in hair regeneration and cashmere yield enhancement.
research In vivo assessment of mechanical properties during axolotl development and regeneration using confocal Brillouin microscopy
This study used confocal Brillouin microscopy to observe that a decrease in tissue compressibility occurs during the development and regeneration of axolotl limbs, suggesting mechanical changes linked to regeneration stages undetectable by fluorescence microscopy.
research The molecular anatomy of cashmere goat hair follicle during cytodifferentiation stage
This study examined the cytodifferentiation stage of hair follicle development in cashmere goats, identifying nine cell populations and key regulatory pathways, including transcription factors and keratin genes, that may influence fiber quality and inform breeding strategies.
research Severe Adult Kerion Celsi With Rapid Improvement During Systemic Antifungal and Adjunctive Secretome Therapy: A Case Report
In this case report, a 48-year-old woman with kerion celsi showed improvement with a regimen including antifungal, bacterial, and adjunctive treatments, though the specific role of mesenchymal stromal cell secretome could not be isolated from the other therapies.
research Development, comparative morphology and cornification of reptilian claws in relation to claws evolution in tetrapods
This study suggests that reptilian claws grow differently from mammalian claws, with continuous epidermal growth rather than a proximal matrix zone for cell proliferation.
research LHX2: a transcription factor in development, homeostasis, repair, and disease
This review synthesizes the diverse roles of the transcription factor LHX2 in development, tissue maintenance, and injury repair across various organ systems, highlighting its potential therapeutic applications and significance in regenerative medicine, particularly in developmental disorders and tissue regeneration.
research Transcriptome Dynamics Reveal Stage-specific and Melatonin-triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus
This study reports that melatonin influences gene expression related to cashmere growth cycles in Inner Mongolian cashmere goats, potentially aiding in understanding and enhancing cashmere yield through molecular regulation.