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Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

New treatments targeting specific genes show promise for treating keratin disorders.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

New treatments for male hypogonadism are effective and should be personalized.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Skin symptoms are important for diagnosing and managing juvenile-onset systemic lupus erythematosus and usually get better with treatment.

Manatee whiskers are specially adapted for touch in water.

Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

FUE provides minimal scarring and quick recovery in hair transplantation, and surgeons not using it may lag in technology.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Low serum complement levels in SLE patients don't always match with disease flares; monitoring C3 and C4 is useful, but cell-bound complement products might better indicate disease activity.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

Combining microsurgery with craniofacial reconstruction improves aesthetic results and reduces harm to the area where tissue is taken from.

Good preoperative assessment is crucial for safe and effective eyelid and brow cosmetic surgery.

A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.

Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.

Facial dark spots can be caused by the sun, genetics, makeup, or medicine, and are diagnosed by patient history and skin tests.

Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Peginterferon alfa-2b and ribavirin therapy for hepatitis C can cause serious side effects, some different from those reported in clinical trials.