Search
for

    Did you mean BRAF Mutation?
    Glossary BRAF Mutation

    mutation in the BRAF gene affects cell growth and division

    A BRAF mutation refers to a change in the BRAF gene, which plays a crucial role in cell growth and division. This mutation can lead to uncontrolled cell proliferation and is often associated with various cancers, including melanoma, colorectal cancer, and thyroid cancer. The most common BRAF mutation is V600E, where valine (V) is replaced by glutamic acid (E) at position 600 in the protein. This mutation can be a target for specific cancer therapies, making it a significant focus in oncology.

    Related Terms

    Sort by

    Research 30 of 361

    1. Lentiginous melanoma. A clinically malignant entity that histopathologically seems benign. Case study harbouring BRAF V 600R mutation Journal of the European Academy of Dermatology and Venereology · 2015 · 1 citations
    2. Hair and nail adverse events during treatment with targeted therapies for metastatic melanoma 2016 · 32 citations
    3. Hair(y) Matters in Melanoma Biology Trends in molecular medicine · 2020 · 7 citations
    4. Diagnosis and Management of Melanoma of the Scalp: A Review of the Literature Clinical, Cosmetic and Investigational Dermatology · 2021 · 3 citations
    5. Is knowledge about the genetic and epigenetic alterations in melanoma a basis for targeted therapy? Experimental Dermatology · 2006
    6. A cross-sectional study of clinical, dermoscopic, histopathological, and molecular patterns of scalp melanoma in patients with or without androgenetic alopecia Scientific Reports · 2022
    7. A cross-sectional study of clinical, dermoscopic, histopathological, and molecular patterns of scalp melanoma in patients with or without androgenetic alopecia 2022
    8. Inflammatory and non-melanocytic tumoral pathology of the nail Pathology · 2014
    9. Dyad of infantile cutaneous and thymic Langerhans cell histiocytosis: Is it rare? Pediatric blood & cancer · 2023
    10. Author response: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes 2020
    11. At the Root: Cutaneous Langerhans Cell Histiocytosis The American Journal of Medicine · 2018 · 3 citations
    12. Decision letter: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes 2020
    13. Genetics of thyroid lesions updated Pathology · 2014
    14. Melanocytes: The new Black The International Journal of Biochemistry & Cell Biology · 2006 · 93 citations
    15. Exploiting the origins of Ras mediated squamous cell carcinoma to develop novel therapeutic interventions Small GTPases · 2011 · 3 citations
    16. Targeted therapy in melanoma Clinics in Dermatology · 2013 · 21 citations
    17. Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells Medical Sciences · 2017 · 37 citations
    18. LB1031 Immune Cell-Mediated Amplification of Stem Cell Activation in Hairy Melanocytic Nevus via Osteopontin-CD44 Axis Journal of Investigative Dermatology · 2024 · 1 citations
    19. Targeting the Warburg Effect in Anaplastic Thyroid Carcinoma: Metabolic Vulnerabilities and Therapeutic Opportunities International Journal of Molecular Sciences · 2026
    20. Natural Compounds Targeting MAPK, PI3K/Akt, and JAK/STAT Signaling in Papillary Thyroid Cancer International Journal of Molecular Sciences · 2025 · 1 citations
    21. America - A Diversity of Life Styles. NJEA Review · 1975
    22. Kinase Inhibition with BAY 43–9006 in Renal Cell Carcinoma Clinical cancer research · 2004 · 234 citations
    23. Biological therapy in the treatment of melanoma Journal of Mind and Medical Sciences · 2018 · 3 citations
    24. Can you diagnose hair loss (Non-scarring alopecia) Pathology · 2014
    25. The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: the Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma Current Dermatology Reports · 2013 · 6 citations
    26. B‐ RAF , naevi and melanoma: a complex relationship British Journal of Dermatology · 2014
    27. Nevus Sebaceus With Novel HRAS Sequence Variant Mutation Misdiagnosed as Alopecia Areata Cutis · 2023
    28. BRAF Inhibitor Dabrafenib in Patients with Metastatic <i>BRAF</i>-Mutant Thyroid Cancer Thyroid · 2014 · 188 citations
    29. Abstract 1677: Epithelial hyperplasia induced by a selective B-Raf inhibitor, WYE-130600 Cancer Research · 2010 · 1 citations
    30. B-Raf and C-Raf Are Required for Melanocyte Stem Cell Self-Maintenance Cell Reports · 2012 · 26 citations