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Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Testosterone therapy increases bone density in older men with low testosterone levels.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Most patients with frontal fibrosing alopecia are postmenopausal women, and treatments like finasteride and dutasteride can improve or stabilize the condition.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The method can effectively extract biomedical information without needing expert annotation, performing better than previous models.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.