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All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

The intensive conventional diet with exercise led to better long-term weight loss and health improvements than the very low calorie diet in obese type 2 diabetics.

The document concludes that careful evaluation is key to diagnose and treat women with hair loss, with tests for thyroid, iron, and hormones as needed.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.

Some systemic treatments work for nail psoriasis but can have serious side effects.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Minoxidil helps hair regrowth in alopecia areata safely.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Using minoxidil on the scalp can help grow hair for people with hereditary baldness.

Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Bimatoprost, a glaucoma medication, may also help treat hair loss.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Giving docetaxel weekly at 40 mg/m² is manageable and has low toxicity for cancer patients.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.