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Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.

Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

The document says menstruation is important for women's health, discusses menstrual disorders, and suggests personalized treatment options.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Menopause can cause skin issues, and seeing a dermatologist helps.

The document suggests a young mother use effective contraception like the Copper-T IUD while considering her health and the need for STD prevention.

The circadian clock in skin cells controls their growth and rest cycles.

Eating certain seeds may help reduce symptoms of Polycystic Ovary Syndrome.

Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.

The document advises health care providers on how to support transgender and gender-diverse youth with appropriate care and referrals.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

The Rotterdam Study aims to understand various diseases in older adults.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Certain genes control the color of human hair by affecting pigment production.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

Newer low-dose oral contraceptives with less androgenic effects improve patient compliance.

The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.