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This study found that protease nexin-1 mRNA is expressed in human dermal papilla cells and is downregulated by dihydrotestosterone in balding scalp, suggesting a role in male-pattern baldness progression.

This study found that the combination of TTNPB and CHIR99021 enhanced the derivation of highly advanced neural stem cells from human pluripotent stem cells, with improved chromatin accessibility and neuroectodermal gene expression, and these cells successfully engrafted in rat hippocampi to ameliorate depression-like symptoms.

In this study, researchers found that NKB placental mRNA expression was higher in women with PCOS, particularly in pregnancies with female offspring, and that NKB expression varied with fetal gender, suggesting a role in PCOS-related placental dysfunction.

This study reports that a new boron/nitrogen-doped carbon nano-onion-based delivery system for doxorubicin enhanced its uptake and anticancer effects in specific cancer cell types, while reducing cardiotoxicity in human heart cells.

People with psoriasis and depression have lower BDNF levels, which could help measure depression in those with psoriasis.

This study found that women with Female Pattern Hair Loss had lower serum BDNF levels, which correlated with higher stress and depression, suggesting BDNF as a potential marker for psychological impacts in these patients.

Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.

This review discusses the regenerative potential of polynucleotides and polydeoxyribonucleotides in aesthetic medicine, noting their benefits for skin texture, hydration, and patient satisfaction despite limited high-quality evidence.

This study found that higher Lnk expression in PCOS patients may contribute to insulin resistance by inhibiting insulin signaling pathways.

Basonuclin helps identify and track hair follicle development and cycling in mice.

This study developed a microneedle system using black phosphorus nanosheets and baicalin for treating androgenetic alopecia, finding it effectively enhanced drug penetration and follicular targeting while showing synergistic efficacy and safety in preclinical tests, including in vivo model efficacy against testosterone-induced hair loss.

In this study, researchers identified a causal link between Epstein-Barr virus infection and clear cell renal cell carcinoma, highlighting GBP1 as a key target and suggesting finasteride as a potential inhibitor, offering a new direction for treatment strategies.

This study found that patients with vitiligo had significantly lower serum BDNF levels compared to healthy controls, which may relate to the condition's etiology or its association with psychiatric disorders.

This study found that combining hair transplantation with platelet-rich plasma treatment significantly improved hair regeneration, reduced hair loss, and minimized skin lesion areas in patients with androgenic alopecia compared to hair transplantation alone, suggesting enhanced treatment efficacy.

This study found that serum APN levels were inversely related to insulin resistance in women with PCOS, suggesting that APN could serve as a clinical marker for insulin resistance in this population.

In this nonrandomized controlled trial, tenon capsule injection of platelet-rich plasma improved capillary perfusion and may enhance short-term vision in patients with acute nonarteritic anterior ischemic optic neuropathy.

This study suggests that NBCCS and BFHS may be the same genetic condition, which could help improve identification and management of misdiagnosed cases with specific surveillance strategies.

This study found that lower serum BDNF levels were associated with higher depression severity and more severe alopecia areata in patients.

This review discusses the concept of drug repositioning and highlights fragmin and protamine as emerging biomaterials for tissue engineering and regenerative medicine, but it reports no new clinical results.

In this study, baseline neutrophil-to-lymphocyte ratio (NLR) was associated with predicting early trichoscopic response in patients undergoing PRP-based treatment for non-scarring alopecia.

This study demonstrated that intradermal treatment with a medical device using Polynucleotides High Purification Technology (PN HPT) significantly improved skin surface, firmness, pigmentation, and radiance in 30 Asian subjects, with benefits lasting up to six months and no adverse events reported.

This study suggests that folliculin, mutated in Birt–Hogg–Dubé syndrome, and its partner FNIP1 may play a role in energy and nutrient sensing through the AMPK and mTOR pathways.

This case report found that a patient with cutaneous polyarteritis nodosa experienced rare and severe manifestations, including digital gangrene and a breast ulcer, requiring aggressive treatment and resulting in below-knee amputation.

Basonuclin is crucial for hair follicle development and cycling in mice.

This study suggests that basonuclin in keratinocytes is likely a regulatory molecule linked to maintaining proliferative capacity and preventing terminal differentiation rather than a cell cycle marker.

This study found that pediatric alopecia areata patients had significantly lower serum BDNF levels compared to healthy controls, which were associated with greater alopecia severity, higher depressive symptoms, and poorer quality of life.

This study concluded that newborn screening for biotinidase deficiency effectively identified cases and likely prevented irreversible complications from the disorder in some infants.

In this study, combining transcranial electrical stimulation with bisphosphonate therapy in patients with postmenopausal osteoporosis resulted in a protective effect on bone collagen synthesis, as indicated by higher P1NP levels over 12 months, compared to bisphosphonates alone.

This study reports that the monoclonal antibody BKN-1 specifically stained basal cell epithelioma cells and certain normal skin structures, indicating a similarity in keratin expression between the tumor and follicular epithelium below the isthmus portion.