November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.
8 citations,
September 2008 in “Medical Hypotheses” The paper suggests that hair loss might be caused by skull growth, not just DHT's effect on hair follicles, and calls for more research.
52 citations,
May 2015 in “PLOS Genetics” miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.
73 citations,
August 2011 in “Stem Cell Research” Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.
December 2016 in “Journal of Pakistan Association of Dermatology” Tissue expansion is a safe primary method for hair restoration in patients with large scalp defects before hair transplantation.
2 citations,
March 2023 in “Annals of Translational Medicine” The analysis shows the U.S. leads in tissue expansion research, mainly for breast reconstruction, with a slightly higher complication rate when using acellular dermal matrix.
3 citations,
August 2018 in “Stem cells international” Hair follicle cells help maintain and support stem cells and blood cell formation.
172 citations,
March 2019 in “The EMBO Journal” FERONIA and LRX proteins help control cell growth in plants by regulating vacuole expansion.
23 citations,
June 2015 in “Journal of Tissue Engineering and Regenerative Medicine” Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.
April 2019 in “Journal of Investigative Dermatology” Eating grape powder may reduce the severity of skin allergy symptoms.
16 citations,
January 2011 in “Archives of Dermatological Research” The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.
11 citations,
December 2018 in “Bone” Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
6 citations,
July 2017 in “Clinics in Plastic Surgery” The document concludes that individualized reconstruction plans are essential for improving function and appearance after head and neck burns.
4 citations,
January 2009 in “Indian Journal of Plastic Surgery” Surgery for scar-related hair loss on the scalp and eyebrow was successful in 75% of patients.
3 citations,
January 2014 in “Elsevier eBooks” Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
The conclusion is that closing scalp wounds is possible, but restoring hair without donor material is still a major challenge.
October 2024 in “Plastic & Reconstructive Surgery Global Open” Tissue expansion is a safe and effective method for scalp hair restoration with high success and patient satisfaction.
June 1997 in “The American Journal of Cosmetic Surgery” Understanding the science of skin stretching is crucial for safe and effective hair replacement techniques.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.
49 citations,
February 2008 in “Stem Cells” Wnt10b helps blood stem cells grow after injury.
2 citations,
January 2017 in “Recent clinical techniques, results, and research in wounds” Using tissue expanders with galeotomies for post-burn alopecia is faster and has fewer complications.
31 citations,
March 2009 in “Archives of Facial Plastic Surgery” The hairline-lowering surgery was effective, safe, and left patients satisfied with few complications.
8 citations,
October 2022 in “Regenerative Therapy” New regenerative treatments for hair loss show promise but need more research for confirmation.
6 citations,
August 2020 in “Cell regeneration” Hair follicle stem cells are similar to bone marrow stem cells but are better for fat cell research.
December 2023 in “The journal of cell biology/The Journal of cell biology” The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.
23 citations,
June 2016 in “FEBS Journal” Boosting β-catenin signaling in certain skin cells can enhance hair growth.
Mesotherapy is effective for treating certain types of hair loss.
45 citations,
June 2018 in “Frontiers in immunology” MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
21 citations,
January 2022 in “Biomaterials Science” RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
43 citations,
December 2013 in “Stem Cells” Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.