research IL6 Is Correlated With Metabolic Syndrome Parameters in Oral Lichen Planus
IL6 is linked to higher risk of heart disease in people with a certain mouth condition.
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research Effect of High-Fructose Diet on the Renal Cortex of Adult Male Albino Rats
High-fructose diets can cause irreversible kidney damage.
research Androgen Therapy in Women: An Endocrine Society Clinical Practice Guideline
The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
research The Pathophysiology of Polycystic Ovary Syndrome
Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
research Protoporphyrin IX: The Good, the Bad, and the Ugly
Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
research The Effects of Transdermal Dihydrotestosterone in the Aging Male: A Prospective, Randomized, Double-Blind Study
Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.
research Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene
A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.
research Global Adiposity and Thickness of Intraperitoneal and Mesenteric Adipose Tissue Depots Are Increased in Women With Polycystic Ovary Syndrome
Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.
research The Cytology and Cytochemistry of the Wool Follicle
Wool follicles are complex, involving interactions between different cell types and structures.
research Role of Cholesterol Sulfate in Epidermal Structure and Function: Lessons from X-Linked Ichthyosis
Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
research Polycystic Ovary Syndrome: Diagnosis and Treatment
PCOS is a common hormonal disorder in women, treated with lifestyle changes and medications like hormonal contraceptives and metformin.
research Low Sex Hormone-Binding Globulin Is Associated With Low High-Density Lipoprotein Cholesterol And Metabolic Syndrome In Women With Polycystic Ovary Syndrome
Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.
research Sex Hormone-Binding Globulin as an Early Biomarker and Therapeutic Target in Polycystic Ovary Syndrome
SHBG may be a useful early indicator and treatment target for PCOS.
research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research Does Prostaglandin D2 Hold the Cure to Male Pattern Baldness?
Prostaglandin D₂ might be targeted for new male pattern baldness treatments.
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Type 2 Diabetes
Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
research Transient Mitochondrial DNA Double Strand Breaks in Mice Cause Accelerated Aging Phenotypes in a ROS-Dependent but p53/p21-Independent Manner
Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
research Steroid 5α-Reductase Inhibitors
New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
research Iron Plays a Certain Role in Patterned Hair Loss
Iron deficiency may contribute to hair loss.
research Impact of Metformin and Rosiglitazone Treatment on Glucose Transporter 4 mRNA Expression in Women with Polycystic Ovary Syndrome
Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.
research The Benefits of Finasteride for Hirsute Women with Polycystic Ovary Syndrome or Idiopathic Hirsutism
Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.
research Contribution of the Hair Follicular Pathway to Total Skin Permeation of Topically Applied and Exposed Chemicals
The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.
research Evaluation of Biophysical Skin Parameters and Assessment of Hair Growth in Patients with Acne Treated with Isotretinoin
Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.
research Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria
Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.
research Insulin Resistance and the Long-Term Consequences of Polycystic Ovary Syndrome
Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.
research Physiological Changes and Dermatoses of Pregnancy
Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.
research Ovarian Hormones and Adrenal Androgens During a Woman's Life Span
Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
research Human Pollution Exposure Correlates With Accelerated Ultrastructural Degradation of Hair Fibers
Pollution exposure speeds up hair damage.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Roles of Steroid Sulfatase in Brain and Other Tissues
Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.