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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Hair loss in men is common, treatable, but not curable.

New effective scar treatments are urgently needed due to the current options' limited success.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Latanoprost can make eyelashes longer, thicker, and darker.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Liposomes could improve how skin care products work but are costly and not very stable.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

One minoxidil-sensitive potassium channel exists in human hair follicles.

No treatment fully prevents hair loss from chemotherapy yet.

Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.

Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Minoxidil and finasteride effectively treat hair loss.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.