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The study developed herbal hair gummies using ingredients like fenugreek, amla, and bhringraj, alongside folic acid, zinc, and biotin, concluding they are palatable, meet quality standards, exhibit antioxidant properties, and may effectively enhance hair growth and reduce hair loss.

Non-drug methods like diet, supplements, and aromatherapy can help manage hair loss and its emotional impact.

This review highlights several natural ingredients, including Citrus Sinensis, Nigella sativa, flax seed, and coconut oil, that may promote hair growth and prevent hair loss due to their protective and nourishing properties, focusing on their formulation into hair serum.

This scoping review reports that preclinical studies suggest omega fatty acids may promote hair follicle growth, but clinical evidence is mixed, with no support for their standalone use in treating alopecia.

This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.

In this study, oral biotin improved hair growth, strength, and combability in a child with uncombable hair syndrome, while hair in two others slowly improved without biotin.

This study found that antibiotic-induced gut dysbiosis, particularly overgrowth of Lactobacillus murinus, can lead to hair loss in mice by depleting biotin.

This review discusses the use of biotin for hair and nail growth, noting clinical improvement in cases with existing pathologies, but concludes there is insufficient evidence supporting its benefits for healthy individuals.

This case report describes a 10-month-old boy with dermatitis, alopecia, and hypotonia who showed dramatic improvement with oral biotin, suggesting a possible defect in biotin absorption or transport.

This study found that 38% of women with hair loss had a biotin deficiency, suggesting oral biotin supplementation should be based on confirmed biotin deficiency rather than as a general treatment.

This review critiques the unwarranted promotion of biotin for hair and nail improvements, noting the lack of evidence for routine use and highlighting concerning trends in consumer and physician practices.

This review discusses two genetic disorders affecting biotin metabolism, each resulting in distinctive skin and hair manifestations, and outlines the associated serious metabolic complications.

This case study of three siblings highlights the importance of recognizing dermatologic signs—alopecia and periorificial dermatitis—for early diagnosis and treatment of biotin-responsive multiple carboxylase deficiency.

This study found that oral biotin supplementation improved outcomes in a mouse model of inflammatory bowel disease by reducing inflammatory cytokine production and enhancing intestinal barrier integrity, suggesting potential therapeutic benefits for IBD patients.

This study found that human keratinocytes express a sodium-dependent multivitamin transporter for biotin, pantothenic acid, and lipoic acid, including a highly specific biotin transport component.

This study reported successful treatment of biotin deficiency in three patients receiving total parenteral nutrition, suggesting current biotin supplementation recommendations may be inadequate to maintain normal biotin status.

This study describes a family with uncombable hair syndrome, suggesting autosomal dominant inheritance, and reports that oral biotin improved hair appearance in two young patients.

This case report describes a 5-month-old Japanese infant with biotin deficiency, where daily oral biotin supplementation led to significant improvements in skin conditions and hair growth.

In this study, two patients with long-term total parenteral nutrition and no biotin intake experienced hair regrowth after biotin supplementation, suggesting biotin deficiency can lead to alopecia.

This study found that an 11-month-old Japanese infant developed biotin deficiency while on a Japanese amino acid formula without biotin, which was resolved with biotin supplementation.

This study found that adding inositol or biotin to a pig's diet without sulfathalidine had no effect on growth or feed efficiency, but both helped alleviate deficiency symptoms caused by sulfathalidine.

In this study, a 54-year-old woman with short bowel syndrome developed biotin deficiency and associated symptoms while on home parenteral nutrition lacking biotin, which improved significantly after supplementation.

This review evaluates biotin's popularity and its purported benefits for hair improvement but finds no clinical evidence supporting its efficacy.

In this study, dietary biotin supplementation showed no significant benefit on reproductive performance in sows or pre-weaning growth and mortality in piglets.

In this study on rats, valproic acid was associated with reduced biotinidase enzyme activity and higher alopecia rates, but biotin supplementation did not significantly affect alopecia occurrence.

This study found that while serum zinc levels were lower in children treated with valproic acid or carbamazepine than in healthy controls, zinc, biotin, and biotinidase enzyme activity remained within normal ranges and unaffected by these treatments.

Biotin deficiency in monkeys causes fur and skin issues, but 20 μg of biotin daily can prevent or cure it.

This study found that temporary hair loss is common after laparoscopic sleeve gastrectomy, and biotin supplementation showed low effectiveness in preventing this hair loss.

This study found that biotin supplementation is common among patients at a dermatology clinic despite a lack of evidence for its dermatologic benefits and potential interference with lab tests.

This study found that male androgenetic alopecia patients had significantly lower serum zinc levels and suboptimal biotin levels compared to healthy controls, suggesting the potential value of zinc and biotin supplementation.