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The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Oxidative stress contributes to hair graying and loss as we age.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

Healthcare providers need better education and policies to serve transgender individuals effectively.

HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.

Certain nutrients can help keep skin healthy as we age.

Injecting cosyntropin into grizzly bears increases blood cortisol but doesn't change hair cortisol levels.

We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.

Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.

ceRNA networks offer potential treatments for skin aging and wound healing.

Stress is likely causing hair loss in Formosan macaques.

Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.

Cosmeceuticals are popular for their skin health benefits and anti-aging effects.

Nitric oxide is important for skin functions and both helps protect against and contributes to skin inflammation and sensitization.

CD4+ skin cells may be precursors to basal cell carcinoma.

New method effectively analyzes finasteride and its stability.

Blue light might help treat skin conditions by affecting the skin's bacteria.

Xiangdong black goats have moderate genetic diversity, minimal inbreeding, and important genes for reproduction, immunity, and other traits.

Histone modification is key in treating chronic inflammatory skin diseases.

Wild African goats have genetic adaptations for surviving harsh desert conditions.