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Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Zinc supplementation may help improve treatment outcomes for chronic hepatitis C.

Acne is an important sign of androgen excess disorders in women.

Potassium levels affect blood sugar and insulin during dialysis, and malnutrition changes children's hair roots.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Testosterone replacement therapy should be used for men with low testosterone levels and symptoms of hypogonadism, after careful diagnosis and considering individual needs.

Proper diet management is crucial for phenylketonuria patients to avoid severe health issues.

Latanoprost eye drops caused excessive hair growth and eyelash whitening in a woman.

A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.

Antioxidants might help prevent pressure ulcers, but more research is needed to find effective ones.

Latanoprost eye drops caused excessive cheek hair growth and eyelash whitening in a woman.

MOF controls skin development by regulating genes for mitochondria and cilia.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

An 80-year-old man with COVID-19 also had constrictive pericarditis, possibly due to an autoimmune or immunoglobulin related disease, and improved after surgery.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Hair growth is cyclic and influenced mainly by local factors.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

The Protein-Sparing Modified Fast is effective for rapid weight loss and maintaining it, but requires medical supervision and can have side effects.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Most patients with hard-to-treat high blood pressure can be managed effectively with various treatments, but no single treatment is perfect.

Insulin resistance linked to obesity may increase COVID-19 severity.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Cyclosporin effectively and safely treated skin diseases in three pets with no side effects.