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A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.

A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

A 63-year-old woman's male-like symptoms were caused by a rare testosterone-producing ovarian tumor, treated by removing her ovaries and fallopian tubes.

Different treatments for PCOS focus on the specific symptoms, with weight loss and lifestyle changes being important.

Ovarian drilling surgery is not clearly better than medical treatments for PCOS symptoms.

Taking biotin can lead to incorrect low results in free testosterone tests.

PCOS treatment should address both symptoms and metabolic risks, starting with lifestyle changes and possibly including medication.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.

A woman's severe hirsutism was caused by Leydig cell tumors in her ovaries, which improved after surgery.

A thorough diagnostic process and teamwork are crucial for managing complex hyperandrogenism in postmenopausal women.

A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.

Ovarian Hyperthecosis caused hypersexuality in an older woman and was successfully treated with surgery.

An 84-year-old woman's hair loss was due to a rare condition called Leydig cell hyperplasia, which was treated with surgery.

A woman's high testosterone levels were caused by a rare ovarian tumor, not the initially diagnosed condition.

Woman with diabetes had hair loss due to rare ovarian tumor; surgery improved hair growth.

A 68-year-old woman developed male traits due to a tumor in her ovary, which was removed, returning her hormone levels to normal.

Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.

Imaging helps detect adrenal gland issues and monitor treatment in congenital adrenal hyperplasia, and can identify tumors affecting fertility.

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

A 71-year-old woman developed male-like features due to high testosterone levels caused by a benign ovarian tumor, which was successfully removed by surgery.

A 72-year-old man with sudden taste issues and hair growth was diagnosed with a severe stomach cancer and died within 5 months.

The conclusion is that thorough investigation of hypertension and hormonal dysfunctions is important, and there may be a link between these conditions and cancer.